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Published on in Vol 15 (2026)

Preprints (earlier versions) of this paper are available at https://preprints.jmir.org/preprint/96501, first published .
Elderly hands texting on a smartphone with a kidney health app open

Effects of a Personalized Retrieval-Augmented Generation Chatbot on Information Needs in Patients With Chronic Kidney Disease: Mixed Methods Randomized Controlled Trial

Effects of a Personalized Retrieval-Augmented Generation Chatbot on Information Needs in Patients With Chronic Kidney Disease: Mixed Methods Randomized Controlled Trial

Hee Jeong Hwang   1 , BS ;   Junghwan Kim   1 , BS ;   Dongseok Heo   2 , BS ;   Jeong Yun You   1 , BS ;   Jeonghwan Lee   3, 4 , PhD ;   Soie Kwon   5, 6 , PhD ;   Kyung Don Yoo   7 , PhD ;   Jung Han Yoon Park   8 , PhD ;   Bongwon Suh   2, 8 , PhD ;   Jung Pyo Lee   3, 4 * , PhD ;   Ki Won Lee   1, 8, 9, 10 * , PhD

1 Department of Agricultural Biotechnology, College of Agriculture and Life Sciences, Seoul National University, Seoul, Seoul, Republic of Korea

2 Interdisciplinary Program in Artificial Intelligence, Seoul National University, Seoul, Seoul, Republic of Korea

3 Department of Internal Medicine, College of Medicine, Seoul National University, Seoul, Seoul, Republic of Korea

4 Department of Internal Medicine, SNUH SMG-SNU Boramae Medical Center, Seoul, Seoul, Republic of Korea

5 Department of Internal Medicine, Chung-Ang University Hospital, Seoul, Seoul, Republic of Korea

6 Department of Internal Medicine, Chung-Ang University, Seoul, Seoul, Republic of Korea

7 Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea

8 Advanced Institutes of Convergence Technology, Seoul National University, Suwon, Gyeonggi-do, Republic of Korea

9 Center for Food and Bio convergence and Bio-MAX Institute, Seoul National University, Seoul, Seoul, Republic of Korea

10 Institutes of Green Bio Science & Technology, Seoul National University, Pyeongchang, Gangwon State, Republic of Korea

*these authors contributed equally

Corresponding Author:

  • Ki Won Lee, PhD
  • Department of Agricultural Biotechnology
  • College of Agriculture and Life Sciences, Seoul National University
  • 1, Gwanak-ro, Gwanak-gu
  • Seoul, Seoul 08826
  • Republic of Korea
  • Phone: 82 10-9986-7464
  • Email: kiwon@snu.ac.kr