Abstract
Background: Digital interventions for obesity have demonstrated efficacy in obesity prevention and management. The emergence of smartphones and ubiquitous apps such as WeChat represents potential modality to enhance the reach, sustainability, and cost-effectiveness of such interventions. By the end of the first quarter of 2024, WeChat had approximately 1.36 billion monthly active users, accounting for 96.5% of China’s population. The use of this platform for obesity interventions has been validated in multiple Chinese trials, most published in Chinese language journals.
Objective: We aim to synthesize the existing evidence on obesity interventions delivered through WeChat to generate implications for future intervention design and development, thereby reaching an international audience.
Methods: We conducted a scoping review of PubMed and China National Knowledge Infrastructure using search terms including “WeChat,” “obesity,” “weight,” “BMI,” “waist circumference,” “hip circumference,” “waist-to-hip ratio,” “body fat,” “skin fold thickness,” and these Chinese equivalents “weixin,” “feipang,” “tizhong,” “tizhongzhishu,” “yaowei,” “tunwei,” “yaotunbi,” “tizhi,” and “pizhehoudu.” We included only original research studies, theses, or dissertations with measurable outcomes that used WeChat functions as intervention strategies. Study quality was assessed using the National Institutes of Health Quality Assessment Tool, with specific tools selected based on study design. Descriptive statistics were applied, with categorical variables summarized as frequencies and percentages (n, %) to report study distribution.
Results: Our scoping review based on PubMed and China National Knowledge Infrastructure identified 665 initial records, among which 43 studies met eligibility criteria and were included for data extraction to characterize intervention details. Results indicated effectiveness in 86.0% (37/43) of studies, with WeChat-assisted obesity interventions achieving significant short- and long-term weight loss measured by objective outcomes (body weight, BMI, waist circumference, hip circumference, waist-to-hip ratio, and body fat percentage). However, formative research informing intervention design was insufficient. Common methodological limitations included lack of randomization and blinding (42/43, 97.7%) and unreported intervention compliance metrics (39/43, 92.0%). Functionally, interventions primarily used “WeChat group” and “Official Account”—public accounts that provide health education, diet or physical activity logging, and other features.
Conclusions: Overall, WeChat represents a promising platform for obesity interventions; however, current apps fail to leverage its full features (eg, online payment and live streaming). Key limitations include methodological heterogeneity and cultural specificity, which were addressed through narrative synthesis stratified by study types. Future research should incorporate the formative phase and use more rigorous methodologies such as randomized controlled trials to optimize intervention design and delivery via this modality.
doi:10.2196/65538
Keywords
Introduction
Obesity is a global health crisis affecting low- and middle-income as well as high-income countries [,]. According to the 2023 Chinese Nutrition and Chronic Diseases Survey, more than 50% of Chinese adults were overweight or obese [], with prevalence rates of nearly 20% among adolescents and 10% in children younger than 6 years []. Obesity is strongly associated with noncommunicable chronic diseases (NCDs), particularly fatty liver, diabetes, hypertension, and dyslipidemia []. Furthermore, NCDs accounted for 90.1% (9.6 million) of deaths and 84.9% (324.6 million) of disability-adjusted life years in China in 2019 []. Wang et al [] project that the prevalence of overweight or obesity in Chinese adults will reach 65.3% (790.0 million) by 2030, potentially leading to a 22.0% (more than CNY 400.0 billion [more than US $60 billion]) increase in total medical costs. In response, the Healthy China Action Plan 2019‐2030 established 15 key strategies, including 11 focused on NCDs intervention []. Thus, implementing evidence-based obesity interventions is critical for preventing future NCD-related mortality.
Although nearly 90% of countries globally have committed to addressing obesity [], the efficacy of interventions for sustained weight control remains limited [,]. Social media platforms are increasingly used in obesity interventions, particularly for health education delivery [,]. Digital health apps can expand geographical reach and overcome barriers to in-person care [], as demonstrated during the COVID-19 pandemic when obesity interventions rapidly shifted toward mobile health (mHealth) solutions []. In the United States, of more than 100,000 available health-related apps, more than 28,000 target weight management []. By late 2023, China had 1.09 billion web users (77.5% penetration) [], with web-based health care users reaching 413.9 million—a 14.2% annual increase []. By reducing medical expenses, improving adherence, and promoting communication between researchers and participants [,], mHealth enables cost-effective and individualized interventions [,]. According to a systematic review about weight management mobile technology, there are a great number of apps designed to facilitate obesity interventions []. For example, Oviva’s NHS Digital–approved app is a convenient way to track weight, keep a food diary, and deliver dietary guidance [-]; Kurbo is an app designed to help teenagers and children aged 8-17 years to lose weight, using the Traffic Light System designed by Stanford University [-]; W8Loss2Go (Weight Loss to Go), implementing a 3-phase approach (identifying problem foods, minimizing eating between meals, and gradually reducing portion sizes), is effective for weight loss []; Weight Watchers Online is a weight loss app that focuses on food, physical activity (PA), sleep, and mindset [,]; and BeHealthy provides education on nutrients, sleep, and yoga []. While designed for weight management guidance and monitoring, few apps incorporate health care professional input or rigorous validation [].
WeChat, a dominant media platform with multiple functions launched by the Tencent Company in China on January 21, 2011, reached 1.359 billion monthly active users in Q1 2024—a 3% increase from March 2023 []. Monthly active user, a key metric reflecting monthly engagement with WeChat services, demonstrates its pervasive adoption. Although initially the primary function of WeChat was chatting, with version updates, WeChat has updated more and more features integrating social networking, mobile payment, and enterprise solutions through features such as Official Account for content dissemination, Mini Program for lightweight apps, and WeChat group for real-time group communication (). The platform’s multifunctional ecosystem facilitates diverse aspects of users’ lives (), including health education delivery [] and chronic disease management [] such as hypertension [,] and diabetes [-].
Although previous studies have summarized the efficacy of mHealth apps for weight management, none have systematically detailed the functional implementation of WeChat in obesity interventions or established evidence-based frameworks for optimizing these functions in future projects. The goal of this study was to conduct a scoping review of existing obesity intervention studies through the WeChat platform and its potential use in future research. We focused on answering the following questions: (1) What WeChat functions have been used in existing obesity prevention or management intervention studies?; (2) What are the primary methodological limitations in these studies?; (3) How can future WeChat-delivered interventions be optimized?

Methods
Search Strategy
To identify literature on WeChat-based obesity interventions up to April 14, 2024, we searched PubMed and China National Knowledge Infrastructure (CNKI, the largest academic database, aggregating more than 95% of officially published Chinese scholarly resources), using the following search terms: “WeChat,” “obesity,” “weight,” “BMI,” “waist circumference (WC),” “hip circumference (HC),” “waist-to-hip ratio (WHR),” “body fat (BF),” “skin fold thickness,” and Chinese equivalent characters: “weixin,” “feipang,” “tizhong,” “tizhongzhishu,” “yaowei,” “tunwei,” “yaotunbi,” “tizhi,” and “pizhehoudu” (Table S1 in ).
Study Selection
After eliminating duplicates and off-topic studies, all the papers that described WeChat-based obesity interventions were screened against the following inclusion criteria: (1) full-text original or empirical human research published in peer-reviewed journals (including trials with or without control groups, and blinded or nonblinded designs); (2) WeChat as primary intervention delivery platform (eg, dietary or PA guidance, dietary or PA diary logging, etc); (3) Chinese degree theses or dissertations from the CNKI dataset; and (4) objective anthropometric outcomes including body weight, BMI, WC, HC, WHR, body fat percentage (BFP), or skin fold thickness. The exclusion criteria included (1) studies using WeChat solely for participant recruitment or follow-up; (2) self-reported anthropometric parameters; and (3) study protocols, animal studies, reviews, patents, books, or inaccessible texts. This process was done by 2 authors (YNW and XXZ) who independently screened titles and abstracts and conducted full-text reviews to identify the final set of eligible papers for inclusion. Any conflicts during this process were resolved through team consensus discussions. The flow diagram was adapted from the official PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) template with modifications specific to our search strategy [].
Data Extraction
The following data were extracted from each study: authors, sample size, presence of control groups, WeChat functions used, interventions duration, outcomes measured, and intervention effectiveness. Intervention effectiveness was categorized as (1) “effective” if all predefined weight-related outcomes (eg, BMI, weight, WC, HC, WHC, BFP, etc) showed statistically significant improvements; (2) “partially effective” if only a subset of predefined outcomes demonstrated significant positive changes; and (3) “not” if none of the predefined outcomes demonstrated significant changes. Themes were synthesized from tile or abstract review followed by full-text review using a blinded, independent dual review process by 2 of the authors (YNW and XXZ). Conflicts were resolved through discussion, with a third author (JG) who would arbitrate unresolved conflicts.
Quality Assessment
A detailed quality assessment was conducted using the Quality Assessment Tool for Controlled Intervention Studies and Before-After (Pre-Post) Studies With No Control Group designed by National Institutes of Health (NIH) []. The assessment tool of controlled intervention studies is applicable to those with control group and intervention strategies, containing 14 items to evaluate the research. Before-after studies refer to those without control groups, instead comparing outcomes of baseline and the end. The tool for before-after studies consists of 12 items. All scoring criteria were evaluated as “yes,” “no,” “not applicable (NA),” or “not reported (NR).” For each item, we assigned 1 point for “yes” and “NA,” zero points for “no” and “NR.” According to the total score, studies were further rated as “good” (10 for controlled intervention studies; 9 for before-after studies), “fair” (5-9 for controlled intervention studies; 5-8 for before-after studies), and “poor” (zero to 4 for both). Two authors (YNW and XXZ) independently completed the quality assessment for each study. Conflicts were resolved via discussion, with a third author (JG) arbitrating unresolved cases.
Statistical Analysis
Statistical analyses were performed using GraphPad Prism 8.4.0 (GraphPad). Descriptive statistics were applied, with categorical variables summarized as frequencies and percentages (n, %) to report study distribution across classifications, as well as the quality assessment outcomes of included studies.
Results
Overview
From the initial 665 papers (67 from PubMed and 598 from CNKI), 12 duplicates and 58 Innovation Achievements of Chinese Science and Technology Project designs were excluded. During the first round of title or abstract review, 236 publications were excluded, in which 26 of them were nonscientific publications, 8 study protocols, 3 animal studies, 10 systematic reviews, 167 nonintervention studies, and 22 conference abstracts. Of the 359 studies undergoing full-text review, 315 (87.7%) were excluded due to the following reasons: focus beyond weight loss or obesity (170, 54.0%), WeChat not used for intervention delivery (45, 14.3%), inadequate WeChat intervention strategy details (8, 2.5%), pregnancy-focused studies (28, 8.9%), and self-reported or unverified measures (65, 20.6%). The flow diagram is shown in . Eight (18.6%) studies [-] were in English with information about study population, control group presence, intervention methods, intervention duration, health outcomes, and intervention effectiveness summarized in . A total of 35 (35/43, 81.4%) studies [-] were in Chinese with study details shown in . Among the 43 studies finally included, 20 (46.5%) [,,-,,,,-,,,-] of them were theses or dissertations. All the studies were conducted in mainland China. None of the papers reported using formative research for intervention development. Sample sizes ranged from 20 [] to 15,310 []. Among the 43 papers, 33 (76.7%) [-,-,-,-,-,-,-] included a control group, and 26 (60.5%) [,,-,-,,,,,,,-,-] reported assigning participants randomly. The duration of interventions spanned 4 weeks [] to 36 months [].

| Authors | Sample | Control group | Intervention related to WeChat | Duration | Outcome | Effective or not |
| Li et al [] | 42 full-time postgraduate students, Shanghai | Yes (randomized) | WeChat: submit PA diaries WeChat group: connect with other participants for social support | 1 month | BW, BFP, WHR, and BMI | Partly effective: BFP |
| Chen et al [] | 102 women from 2 community health centers in Changsha | Yes (randomized) | WeChat: set up fruit or vegetable intake goals and daily steps, educational modules along with tailored tips and messages, and messages to encourage and reinforce positive behavioral changes | 6 months | WC and BMI | Not |
| Han et al [] | 120 overweight and obese patients with T2DM from a hospital in Nanjing | Yes (randomized) | Official Account: information (video teaching, compulsory course, and Monday paper); function (diet form, resistance or aerobic exercise, body measurement, and homework feedback) | 12 months | BMI, WC, HC, WHR, and BFP | Partly effective: BMI |
| Xia et al [] | 343 participants with T2DM | Yes (randomized) | WeChat group: post BG test result, completion of exercises, medication, self-management data WeChat voice call: weekly and monthly summaries to participants | 6 months | BW and BMI | Partly effective: BW |
| Yang et al [] | 977 overweight patients from a hospital in Zhejiang | No (before-after) | WeChat group: report anthropometry (eg, body weight), daily dietary intakes, and PA Mini Program: report body weight WeChat: personal feedback on weight management | 36 months | BW | Effective |
| Ling et al [] | 300 inpatients with primary hypertension in a hospital in Xi’an | Yes (randomized) | Official Account: posthypertension-related knowledge WeChat group: posthypertension-related knowledge; distribute information about educational lectures One-to-one chatting: answer questions | 1 month | BMI and WC | Not |
| Liu et al [] | 300 overweight or obese participants in Sichuan | No (before-after) | WeChat: postdinner plates and beverage | 3 months | BW, BMI, WC, BFP, and WHR | Effective |
| He et al [] | 15,310 occupational participants in the Shunyi District of Beijing | Yes (those did not follow the Official Account) | Official Account: Health education including intervention of PA and diet | 6 months | BW | Partly effective: males |
aThere were favorable changes in the indices after intervention according to their own reports in the study.
bPA: physical activity.
cBW: body weight.
dBFP: body fat percentage.
eWHR: waist-to-hip ratio.
fWC: waist circumference.
gT2DM: type 2 diabetes mellitus.
hHC: hip circumference.
| Authors | Sample size | Control group | Intervention related to WeChat | Duration | Outcome | Effective or not |
| Yinbao [] | 1840 from the 51st Regiment of the Third Division in Xinjiang | Yes (randomized) | Official account: post health knowledge | 12 months | BW, WC, HC, and BMI | Partly effective: HC and BMI |
| Lu [] | 62 patients with coronary heart disease in a hospital in Tangshan | Yes (randomized) | Mini Program: record diets WeChat group: supervise diet, share educational material, and healthy diet competitions WeChat live streaming: educational lectures | 3 months | BW, BMI, and WC | Partly effective: BW and BMI |
| Youxuan [] | 295 people at high risk of hypertension from 15 communities in Haikou | Yes (randomized) | WeChat group: reminding to upload diet and PA, upload health education, and health guidance | 12 months | BMI, WC, and HC | Effective |
| Jun [] | 60 patients with prediabetes aged 50‐70 years from a health management center, Guangzhou | Yes (randomized) | WeChat group: share heart rate data, remind to practice, and communication to promote PA | 3 months | BW and BFP | Effective |
| Linjuan [] | 165 patients with T2DM from a hospital in Inner Mongolia | No (before-after) | Mini Program: record glucose, evaluate diet, daily step recording, nutrition recipe, health knowledge, and remind medicine intake | 6 months | BMI | Effective |
| Tianmeng et al [] | 1292 residents with higher blood pressure in Shandong | No (before-after) | WeChat group: post poster or papers about health knowledge; answer daily questions | 3 months (100 days) | WC, HC, BW, BMI, and BFP | Effective |
| Mengqin [] | 480 patients with essential hypertension aged 18–70 years from 5 towns in rural areas of Shanxi | Yes (randomized) | WeChat group: post health knowledge of posters, papers, and videos | 3 months | BMI, WC | Not |
| Wei et al [] | 200 students with normal blood pressure enrolled in 2017 from a university in Xizang | Yes (randomized) | WeChat group: post health education of essays, cartoon, pictures, videos One-to-one chatting: provide consultancy | 6 months | BMI | Effective |
| Ruixue et ali [] | 63 patients with overweight or obesity from a hospital in Chongqing | No (before-after) | WeChat group: post health knowledge, upload personal PA recording, communications among participants, and upload daily diet recording and evaluated by physicians | 3 months | BW, BMI, BFP, and WC | Effective |
| Lu [] | 152 patients with diabetes from 5 communities in Shenzhen | Yes (randomized) | WeChat group: post health knowledge, discussion, and evaluation on nutrition | 3 months | BMI and WC | Effective |
| Xiaoyuan et al [] | 100 patients with phlegm dampness constitution coronary heart disease from a hospital in Nanning | Yes (randomized) | WeRun: record daily steps WeChat group: supervise daily diet and PA | 6 months | BW, WC, and BMI | Effective |
| Zihao et al [] | 54 overweight or obese people from a hospital in Guizhou | No (before-after) | WeChat group: supervise and provide guidance for daily diets and PA; answer questions of participants | 3 months | BW, WC, HC, and BFP | Effective |
| Weiwei [] | 68 older adult patients with chronic diseases with physical inactivity in 2 communities in Bengbu | Yes (participants from Hubin) | WeChat group: post health education of materials, upload weekly PA recording, and health guidance | 6 months | BMI and WHR | Effective |
| Jinhua [] | 107 older adult patients with hypertension from 4 communities in Changsha | Yes (randomized) | WeChat group: share healthy diet and PA videos, upload healthy knowledge about hypertension, and web-based consultancy | 6 months | BMI and WC | Partly effective: BMI |
| Peijun [] | 120 patients with obesity who underwent physical examination from Sichuan University | Yes (randomized) | WeChat group: post health education materials One-to-one chatting: answer questions Official Account: Traditional Chinese Medicine Health Preservation Special Issue | 6 months | BW, BMI, BFP, and WHR | Effective |
| Jielili [] | 48 cases of obesity from Jinglao Community, Hetian | Yes (obesity and normal weight control) | WeChat group: health education; psychological cognition, and weight management | 3 months | BW, WC, and HC | Effective |
| Ziwei [] | 40 young and middle-aged patients with hypertension from 3 community health care centers in Hengyang | Yes (randomized) | WeChat group: upload health education, share BMI and WC change to encourage each other, supervise daily steps, guidance on smoking and drinking, remind on medicine intake, and share music and videos to relax | 6 months | BMI and WC | Partly effective: BMI |
| Yuepeng [] | 40 patients with hyperuricemia in a Tianjin hospital | Yes (randomized) | Official Account: education on diet, PA, and medication knowledge WeChat group: post health education contents, share videos of PA, and answer questions | 6 months | BW, WC, HC, BMI, and WHR | Not |
| Xi et al [] | 47 employees in an affiliated hospital | No (before-after) | WeChat group: share pictures of daily diets and PA; one-to-one dietary guidance by professional nutritionist (including intervention of PA and diet) | 1.5 months | BW, BMI, BF, BFP, and WC | Effective |
| Jianxin et al [] | 130 older adult hypertensive patients from Chinese PLA Hospital No. 305 | Yes (not randomized, grouped by first clinic date) | Mini Program: diagnosis and treatment, medication guidance, and data management | 6 months | BW, BMI, WC, WHR, and BFP | Partly effective except BW |
| Li [] | 100 patients with T2DM from community health service center in Chongqing | Yes (randomized) | Official Account: guidance on personal diet and PAs; upload situation of dietary, PA, glucose, and blood pressure; and supervision and health education | 12 months | BW, BMI, WC, HC, and BFP | Effective |
| Yingming [] | 60 patients with overweight or obesity and polycystic ovary syndrome from 2 hospitals in Hainan | Yes (not randomized, grouped by first clinic date) | WeChat group: experience sharing, life behavior guidance, and supervision | 3 months | BW, BMI, WC, HC, and WHR | Partly effective except HC |
| Lijuan [] | 100 young and middle-aged patients with hypertension from all community health service centers in Fuding | Yes (randomized) | WeChat group: health education, consultancy by a doctor, and remind of changing unhealthy timetable | 6 months | BW, WC, HC, and BMI | Not |
| Jiawei [] | 128 patients with T2DM treated or hospitalized in a hospital, Chengdu | Yes (randomly) | Official Account: post intervention strategies, collect information WeChat group: share intervention strategies | 3 months | WHR | Effective |
| Yuexi et al [] | 60 residents with prediabetes from a hospital in Nanning | Yes (randomly) | WeChat group: upload health knowledge, answer questions | 24 months | WC and BW | Effective |
| Jingxia et al [] | 278 employees from 4 worksites in Yang River Delta | Yes (randomly select 2 worksites) | Official Account: post information about obesity, diet and PA, querying energy of food, querying PAs, web-based competition on daily diet, and PAs with rewards | 12 months | BW, BMI, WC, HC, and WHR | Partly effective: BW, BMI, and HC |
| Rongrong [] | 314 individuals with prediabetes diagnosed by a hospital in Shandong | Yes (randomly) | Official Account: health education WeRun: supervise daily steps WeChat group: health lectures and health educations in voice, words, and pictures | 7.5 months | BW, BMI, WC, and HC | Effective |
| Xujuan et al [] | 36 people with obesity from a physical examination center in Taiyuan | No (before-after) | WeChat group: exercise prescription | 2 months | WC, BW, BMI, and BFP | Effective |
| Xiao and Dafang [] | 301 volunteers | No (before-after) | WeChat group: provide guidance on diet, PAs, and psychology | 1 month | BW | Effective |
| Xiaojuan et al [] | 20 overweight patients with prediabetes from a hospital in Wuxi | No (before-after) | WeChat group: upload health knowledge, share daily food and energy intake, and answer questions | 6 months | BW, BMI, and WC | Effective |
| Bei [] | 262 middle-aged and young patients with primary hypertension from a community health service center in Urumqi | Yes (randomly) | WeChat group: upload health education material weekly, answer questions during intervention, and communicate with other participants | 6 months | BMI | Not |
| Huirong et al [] | 223 patients with chronic noninfectious diseases from a hospital in Xinjiang | Yes (Randomly) | Official Account: Public Health Microworld | 3 months | BW, BMI, WC, HC, WHR | Effective |
| Di [] | 40 obesity children aged 10‐11 from one of primary school in Beijing | Yes (randomly) | WeChat group: share pictures of 3 meals of children; upload web-based education materials (including PA and diet) | 2 months | BW, BMI, WC, HC, and BFP | Partly effective: BW and BMI |
| Jiangping et al [] | 77 college teachers from 2 universities in Harbin | Yes (1 university) | WeChat group: upload health education and share PAs videos | 3 months | BMI and WC | Effective |
| Dongmei et al [] | 86 coronary heart disease patients from a hospital in Shandong | Yes (Randomly) | WeChat group: upload health education, supervise participants to follow personal treatment, and communicate with others | 12 months | BMI | Effective |
aThere were favorable changes in the indices after intervention according to their own reports in the study.
bThesis for degree (master\'s and PhD).
cBW: body weight.
dWC: waist circumference.
eHC: hip circumference.
fPA: physical activity.
gBFP: body fat percentage.
hT2DM: type 2 diabetes mellitus.
iWHR: waist-to-hip ratio.
Methods of Intervention
Among the 43 papers ultimately included, 32 (74.4%) [-,,-,,-,-,-,-] used a single WeChat function for interventions, while 11 (25.6%) [,,,,,,,,,,] used multiple functions of WeChat to implement their intervention studies. “WeChat group” and “Official Account” were 2 functions used the most, with 33 (76.7%) [,,,,-,-,-,-,,] and 11 (25.6%) [,,,-,,,,,] studies using them, respectively (). WeChat groups primarily facilitated communication between investigators and participants. Official Accounts were mainly used to deliver dietary or PA education and record daily diets and PA. Four (9.3%) studies [,,,] used Mini Program in their intervention strategies with similar but expanded functions as Official Account. Three (7.0%) studies [,,] used one-to-one chatting functions enabling confidential consultations. In addition, 2 (4.7%) studies [,] used WeRun to conduct interventions. Meanwhile, another 2 used voice call [] and live streaming [] separately. A total of 4 (9.3%) studies did not clearly report the specific functions of WeChat they used in their intervention (refer to “Intervention” item in and for more details).
| Function | Definition | Values, n (%) |
| WeChat Group | Containing up to 500 members; all the members can share information and chat in the group; daily attendance of web-based activities | 33 (76.7) |
| Official Account (accounts that developers or merchants apply for on the WeChat official platform) | The platform uses communication and interaction with specific groups of text, pictures, voice, and video, forming a mainstream online and offline WeChat interactive marketing Way | 11 (25.6) |
| Mini Program | Lightweight apps that run within the WeChat environment; smaller than dedicated apps; no need to download | 4 (9.3) |
| One-to-One Chatting | Sending text messages and voice messages; making video calls and voice calls; sharing pictures or WeChat public press paper; transferring money to WeChat friends | 3 (7.0) |
| WeRun | Recording the number of daily steps taken in walking | 2 (4.7) |
| Voice Call | Free communicating method with your WeChat account followers under network environment | 1 (2.3) |
| WeChat Live Streaming | Directly get access to live streams within WeChat without additional download; providing real-time interaction, content sharing, and more | 1 (2.3) |
| Not specified | Did not mention which specific functions were used for intervention | 4 (9.3) |
Descriptive Statistics on Intervention Efficacy
In summary, 25 out of 43 (58.1%) studies [,-,,,,-,-,-,] demonstrated significant improvement across all obesity-related measures. Of the studies remaining, 12 (27.9%) [,,,,,,-,,,] showed partial effectiveness on the selected measures and 6 (14.0%) [,,,,,] reported no significant effects with a duration period no longer than 6 months. BMI was the most commonly used outcome measure for obesity, in which 27 (77.1%) [,,,,,,,-,,-,-,] out of 35 [,-,,-,-,,-,-,] were significantly decreased after intervention. A total of 28 (65.1%) studies [,,,,,,,,-,,,-,,,,,-] assessed body weight, in which 23 (82.1%) [,,,,,,,-,,,,,,,,,,,] showed weight loss after intervention. A total of 30 (69.8%) studies [,,,,,,,,-,,,-,,,-,] assessed WC as outcome, in which 18 (60.0%) [,,,,-,,,,,-,,,,] of them showed a significant reduction after intervention. For HC, a total of 14 (32.6%) studies [,,-,,,,,,,,,] were considered it as outcome, in which 9 (64.3%) [,,,,,,,,] showed significant decrease. Similarly, a total of 11 (25.6%) studies [-,,,,,,,,] assessed WHR as outcome, in which 7 (63.6%) [,,,,,,] of them showed a significant decrease at the end of the study. Of the 14 (32.6%) studies [-,,,,,,-,,] assessing BF, only 1 (7.1%) [] of them used BF and all others used BFP. BF and BFP were shown to be impacted mostly by interventions compared with other measures in these studies because 12 (85.7%) [,,,,,,,,,,] out of 14 [-,,,,,,-,,] showed that they were significantly decreased ( and ).
Quality Assessment of Study
Using the NIH Study Quality Assessment Tool, we assessed a total of 33 studies [-,-,-,-,-,-,-] that had a control group, with 4 (12.1%) [,,,] rated as good quality, 25 (75.8%) [,,,,-,-,,,,-] as fair quality, and 4 (12.1%) [,,,] as poor (See Table S2 in ). The number of studies meeting each assessment item is shown in . Twenty-seven (81.8%) [,,-,-,,,,,-,,,-] of them were described as randomized, in which 16 (59.3%) [,,-,,,,,,,,,] reported randomization methods that were regarded as adequate (see Table S2 in , item 11 and item 22). Only 2 (6.1%) studies [,] reported using a double-blinded randomization process, and only 1 (3.0%) study [] reported that outcome assessors were blinded. Among all the studies with control groups, 6 (18.2%) [,,,,,] did not report demographic information separately for intervention and control groups, and 4 (12.1%) studies [,,,] reported significant differences in some demographic or other factors related to the outcome being assessed (see Table S2 in , item 6). Two (6.1%) studies [,] reported an overall dropout rate exceeding 20%, with exact values of 23.1% [] and 28.4% [] separately, and 4 (12.1%) studies [,,,] provided no information about dropout rate (see Table S2 in , item 7). In addition, 3 studies reported high intervention adherence [,,], while 3 others reported low adherence [,,]. Besides, intent-to-treat analysis was used in data analysis in 3 studies to avoid bias caused by dropout [,,].
A total of 10 out of 43 (23.3%) studies [,-,,,,,] used a before-after design without a control group. According to the rating, all of them [,-,,,,,] were rated as fair quality (Table S3 in ). The number of studies meeting each assessment item is shown in . All the before-after studies [,-,,,,,] stated research questions or objectives clearly and presented specific inclusion and exclusion criteria. Two (20.0%) studies [,] included participants who could represent the population who would be eligible, and 1 (10.0%) study [] enrolled all the eligible participants meeting the entry criteria. Although some of the studies [,,,,] provided information about sample size calculations and power to detect statistical differences, they claimed insufficient power as a limitation. All the studies [,-,,,,,] clearly and consistently described intervention strategies and used effective and objective outcome measurements. However, none reported whether blinding was used during intervention implementation or data analysis. All studies [,-,,,,,] prespecified outcome measures, which were applied clearly and consistently throughout the study process. Three studies reported a loss to follow-up rate exceeding 20%, with rates of 82.4% [], 24.3% [], and 55.5% [], respectively. All studies [,-,,,,,] analyzed changes in outcomes of interest before and after the intervention and presented P values, but only 3 studies [,,] measured outcomes multiple times before, during, and after the intervention. None of these studies was conducted at the group level; thus, it was not applicable to account for the use of individual-level data in determining group-level effects in the statistical analysis.
| Assessment item | Values, n (%) |
| Outcomes valid and reliable | 33 (100.0) |
| Outcome prespecified | 33 (100.0) |
| Dropout rate between groups | 29 (87.9) |
| Randomized controlled trial | 27 (81.8) |
| Overall dropout rate | 27 (81.8) |
| Groups similar | 23 (69.7) |
| Randomization adequate | 16 (48.5) |
| Treatment allocation concealed | 15 (45.5) |
| Sample size enough | 11 (33.3) |
| Other interventions avoided | 6 (18.2) |
| High adherence | 3 (9.1) |
| ITT analysis | 3 (9.1) |
| Participants and providers blinded | 2 (6.1) |
| Analyst blinded | 1 (3.0) |
aITT: intention-to-treat.
| Assessment item | Value, n (%) |
| Objective clearly stated | 10 (100.0) |
| Eligibility criteria clear | 10 (100.0) |
| Intervention clear and consistent | 10 (100.0) |
| Outcomes assessment | 10 (100.0) |
| Analyze changes with P value | 10 (100.0) |
| Follow-up rate | 5 (50.0) |
| Outcomes measured multiple times | 3 (30.0) |
| Participants representative | 2 (20.0) |
| All eligible participants enrolled | 1 (10.0) |
Discussion
Principal Findings
This is the first publication to describe intervention studies focused on weight loss or obesity control conducted via WeChat. We identified gaps in the current design and implementation of these digital intervention studies, such as inadequate tracking options and social support, lack of individualized goals, and absence of health care experts []. Overall, the results are promising, suggesting that WeChat may be an effective platform for supporting weight loss or obesity management. However, more rigorous, randomized controlled trials are needed to understand the effectiveness of interventions delivered using this platform, and to determine the best implementation strategies. Our research revealed several important findings.
Deficiency of Current Obesity Interventions via WeChat
None of the studies reported using formative research to design the intervention. Formative research is a process of collecting useful data about the targeted population and context before or during intervention implementation, during which behavioral change strategies are developed and refined to be maximally suitable []. This process helps with cultural contextualization and optimizes the impact of intervention strategies [] by generating more effective interventions tailored to specific populations. For example, formative research on diabetes management and support indicated that intervention strategies for type 1 diabetes should be different from those for type 2 []. Thus, to better use WeChat in obesity intervention studies, formative research is imperative for developing further strategies to achieve weight management outcomes. Of the 6 studies [,,,,,] that reported no significant changes in obesity-related measures, all had a duration of less than 6 months. Intervention durations of 6-12 months and higher contact hours were correlated with more substantial changes [,]. Thus, future studies should consider extending intervention duration and enhance contact hours.
According to the assessment of studies using the Quality Assessment Tool designed by NIH [], most studies had insufficient sample sizes. The intervention studies conducted in Chinese populations also had several common limitations. First, although most studies used randomization to assign participants to groups, blinding was rarely used (more than 95% did not report blinding during the intervention process). Similarly, information about participant adherence to interventions was limited, which impeded evaluation of effectiveness. In addition, our review of the inclusion and exclusion criteria found that most studies did not control for confounding effects caused by simultaneous participation in other intervention studies. These limitations might cast doubt on the generalizability of the findings.
Majority WeChat Functions Used in Current Research
WeChat, one of the most widely used social media platforms in China, has many functions that can facilitate obesity interventions [,]. In recent years, more intervention studies have used WeChat as a tool in China [,-] because of its convenience and wide reach. The Official Account and WeChat group were the most common features used in the intervention trials included in this review. Both one-to-one chatting and WeChat groups facilitated immediate communication. Although this type of immediate communication might occupy researchers’ time, it can also provide quick assistance to participants, potentially reducing loss to follow-up and increasing adherence to interventions, which may lead to positive outcomes. Official Account and Mini Program are user-friendly ways to disseminate intervention-related information, such as health knowledge and PA courses, as well as to record and evaluate personal data on daily diet and PA. While these functions could help researchers deliver health-related information, they do not ensure that participants actually engage with this information.
Generally, WeChat platform shows promise for obesity interventions; however, its utilization for health promotion still needs to be optimized. For example, although researchers can send intervention materials to participants easily via WeChat, there is no guarantee that they will pay attention to the health messages received []. Thus, study coordinators should not only use WeChat to deliver health-related information but also try to improve participant engagement through compelling content and strategies to compete for attention with the vast amount of the information disseminated through digital platforms [].
Future Directions—Use of WeChat in Future Obesity Intervention Research
Online Payment
To date, no study has incorporated the online payment function of WeChat into existing obesity interventions. A potential strategy could involve offering time-limited discounts on healthy foods (such as vegetables and fruits) to incentivize participants. Financial incentives have been shown to promote participants’ adherence and enhance the effectiveness of interventions []. Studies targeting obesity or overweight populations for weight loss indicated that financial incentives can motivate healthy behaviors and facilitate weight loss [-].
Living Streaming
WeChat’s live streaming function could encourage better engagement during health education. Because of the widespread transmission of the COVID-19 pandemic, people were required to quarantine at home and public places, such as parks and gyms, were closed, resulting in physical inactivity []. In view of this situation, the Chinese government expressed encouragement and support for live-streaming fitness in its National Fitness Plan (2021‐2025) []. Genghong Liu’s (a Taiwanese singer) free live-streamed exercise sessions on Douyin (the Chinese version of TikTok) attracted more than 13.9 billion viewers on April 17, 2022 []. This demonstrates the potential opportunity and serves as inspiration for using WeChat’s live-streaming function to provide guidance on weight control.
Peer Support
Based on our review of intervention strategies in the included studies, WeChat group function served as a platform on which participants could communicate with each other to exchange experience and thoughts and provide peer support as well as encouragement [,,,,]. Group support in a study using Noom, an app for obesity intervention, demonstrated positive impacts of peer support within the group, including enhanced health education acquisition (such as reading and responding to health-themed information) and increased responses to others’ posts []. Evidence from Noom highlights the importance of social support, especially peer support, for future WeChat intervention studies.
Target Population
Although WeChat users are very diverse, older adults and young people, individuals with low education levels, and those living in poverty-stricken areas, many of whom are nonnetizens, still face difficulties using multiple WeChat functions or even accessing the platform []. Thus, implementing WeChat-based interventions among these populations might be limited.
Limitations
Our review has several limitations. First, methodological heterogeneity and variable reporting quality in Chinese language studies limited the direct comparability of outcomes, but we addressed this using narrative synthesis by study type (with or without a control group). Second, while the cultural specificity of WeChat-based interventions limits generalizability, this review lays important groundwork for cross-platform comparisons.
Conclusions
In summary, WeChat is a potential platform for delivering obesity interventions due to its wide use and various functions. Most of the reviewed papers reported effectiveness in terms of weight loss. However, intervention studies conducted via WeChat were limited in design and evaluation rigor. Therefore, future studies should include formative research for intervention development, use a randomized controlled blinded design, and use objective obesity outcome measures to increase the reliability of their findings. The main features of WeChat used in the included obesity interventions enabled chatting and information sharing without spatial limitation. Thus, further studies should explore multiple functions simultaneously to enhance participant engagement with health education materials, examine the impact of varying exposure levels, and increase participant engagement.
Acknowledgments
The authors attest that there was no use of generative artificial intelligence technology in the generation of text, figures, or other informational content of this manuscript.
Data Availability
No new datasets were created in this scoping review. The manuscript synthesizes data from previously published studies (-).
Authors' Contributions
JG was in charge of the investigation process, project administration, and supervision. JG and YW conceptualized the study. YW and XZ worked on the data curation. YW conducted the formal analysis, while JG and YW worked on the design of methodology. YW worked on the visualization and original draft. All the authors contributed to the manuscript review and editing. All authors approved the final version of the manuscript.
Conflicts of Interest
None declared.
Search terms and quality assessment.
DOCX File, 45 KBPRISMA-ScR checklist.
DOCX File, 110 KBReferences
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Abbreviations
| BF: body fat |
| BFP: body fat percentage |
| CNKI: China National Knowledge Infrastructure |
| HC: hip circumference |
| mHealth: mobile health |
| NCD: noncommunicable chronic diseases |
| NIH: National Institutes of Health |
| NR: not report |
| PA: physical activity |
| PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses |
| WC: waist circumference |
| WHR: waist-to-hip ratio |
Edited by Taiane de Azevedo Cardoso; submitted 21.Aug.2024; peer-reviewed by Janice Chan, Ke Yun; final revised version received 30.Jun.2025; accepted 11.Jul.2025; published 11.Dec.2025.
Copyright© Yinuo Wang, Xuxiu Zhuang, Samantha Sundermeir, Joel Gittelsohn. Originally published in the Interactive Journal of Medical Research (https://www.i-jmr.org/), 11.Dec.2025.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Interactive Journal of Medical Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.i-jmr.org/, as well as this copyright and license information must be included.

