Published on in Vol 9, No 4 (2020): Oct-Dec

Preprints (earlier versions) of this paper are available at, first published .
Prevalence of and Factors Associated With Eustachian Tube Dysfunction Among the Public in Jeddah, Saudi Arabia: Cross-Sectional Survey-Based Study

Prevalence of and Factors Associated With Eustachian Tube Dysfunction Among the Public in Jeddah, Saudi Arabia: Cross-Sectional Survey-Based Study

Prevalence of and Factors Associated With Eustachian Tube Dysfunction Among the Public in Jeddah, Saudi Arabia: Cross-Sectional Survey-Based Study

Original Paper

1Otorhinolaryngology and Head and Neck Surgery, King Abdulaziz University, Jeddah, Saudi Arabia

2Otorhinolaryngology and Head and Neck Surgery, Prince Mansour Military Hospital, Taif, Saudi Arabia

*all authors contributed equally

Corresponding Author:

Khalid A Alshehri, MD

Otorhinolaryngology and Head and Neck Surgery

King Abdulaziz University

PO box 80200

Jeddah, 21589

Saudi Arabia

Phone: 966 567033721


Background: Obstruction of the Eustachian tube is a common condition that is unpleasant and might lead to various middle ear disorders.

Objective: This study aimed to estimate the prevalence of Eustachian tube dysfunction (ETD) among the public in Jeddah, Saudi Arabia.

Methods: This cross-sectional survey-based study was conducted in Jeddah during August 2018 by distributing an electronic survey form to participants from different districts of the city. All male and female residents of Jeddah aged 10 years and above had the chance to participate in this study.

Results: A total of 2372 participants (female, 1535/2372, 64.71%; male, 837/2372, 35.28%; mean age 31.31 years, SD 11.85 years) agreed to contribute to our study. Upon analysis of their answers to the questionnaire, the overall prevalence of ETD in our sample was found to be 42.49% (1008/2372). The prevalence was higher among participants who reported a previous diagnosis of ETD and hearing loss (1897/2372, 80.00% and 1902/2372, 80.21%, respectively). Additionally, participants with a family history of hearing loss had a significantly higher prevalence (1136/2372, 47.92%) of ETD than those with no family history of hearing loss. Our analysis also showed that females were at a greater risk of developing ETD than males (P=.01).

Conclusions: As per our prevalence data, ETD is a common disease in Jeddah, pointing to the need for more attention, awareness, and research.

Interact J Med Res 2020;9(4):e14640



The Eustachian tube is a thin tube that links the middle ear with the nasopharynx. It is responsible for ventilation and pressure equalization in the middle ear [1]. Therefore, any dysfunction of the Eustachian canal may lead to impaired sound conduction. Eustachian tube obstruction is a common condition that is unpleasant and might lead to various middle ear disorders such as chronic otitis media (OM) and cholesteatoma [2]. Eustachian tube dysfunction (ETD) can be due to intrinsic causes such as anatomical anomalies in the cleft palate, or acquired and extrinsic factors such as an allergic response at the site of the Eustachian tube opening, a viral upper respiratory tract infection, or a combination of intrinsic and extrinsic factors [3].

The prevalence of ETD among the adult general population is approximately 1% [4], and around 40% of children develop at least transient ETD [5]. Several studies have determined that ETD exists in up to 70% of patients undergoing tympanoplasty for middle ear disorders such as cholesteatoma and chronic OM [6,7]. A recent study conducted in the United States assessed the burden of ETD and determined that the condition is related to more than 2 million clinic visits per year among patients aged 20 years and above [8]. Some possible consequences of ETD include communication problems, decreased productivity, and poor quality of life. One of the main consequences of ETD is OM with effusion (OME), which is a common cause of hearing loss and is related to speech delay among children [9].

Patients with ETD complain of ear fullness, pain, muffled hearing, “popping” sounds, or tinnitus [6]. Hence, to diagnose ETD, a patient must exhibit the abovementioned symptoms of pressure disequilibrium in the involved ear. Nonetheless, it has always been challenging to identify appropriate diagnostic methods and tests as well as establish criteria for identifying individuals with ETD [6]. Several tools have been reported for evaluating Eustachian tube function. However, the use of Eustachian tube function tests is limited by the requirement of expensive tools and trained staff, which are commonly available in specialized health centers only [10]. Thus, a simple instrument such as a questionnaire that can reliably identify individuals with ETD would be a helpful tool for in-office practice, since it is the most appropriate way to self-evaluate a patient’s complaints and symptoms. The 7-item Eustachian Tube Dysfunction Questionnaire (ETDQ-7) is considered to be a disease-specific instrument for evaluation of the symptoms associated with obstructive ETD and its treatment outcomes [11].

Knowledge of the prevalence of a disease within a population is of value in establishing possible current and future community service requirements. To the best of our knowledge, no study in Saudi Arabia has assessed the prevalence of ETD in the community to date. This study aims to evaluate the prevalence of ETD in Jeddah, Saudi Arabia, by using the ETDQ-7 instrument.


This study was approved by the institutional review board of King Abdulaziz University Hospital, Saudi Arabia. This cross-sectional survey-based study was conducted by distributing an electronic questionnaire among the general population of Jeddah during August 2018. The electronic questionnaire only accepted a one-time response per participant so that there would be no instances of multiple responses from the same person. Jeddah, an urban metropolis and one of the biggest cities in Saudi Arabia, is located in the western region of the country and has a population of approximately 3.5 million.


This study aimed to estimate the prevalence of ETD in all areas of Jeddah. An electronic survey form was distributed by trained medical students to the participants. Randomly distributed city districts were selected for the study in order to obtain a realistic representative sample of the population of Jeddah, taking into account the more densely populated northern and southern regions of the city. All male and female residents of Jeddah aged 10 years and above had the chance to participate in this study. The purpose of the study was disclosed to the participants, and written consent was obtained before they could fill out the questionnaire.


The ETDQ-7, designed by McCoul et al [11] 5 years prior to this study, was established as a new scoring system for the evaluation of the symptoms associated with obstructive ETD [11]. Each of the 7 items have scores ranging from a minimum of 1 to a maximum of 7 points, resulting in a total score of between 7 and 49 points. A total score≥14.5 or a mean score≥2.5 is considered abnormal, with higher scores indicating a greater level of symptom severity.

The ETDQ-7 is a valid measure [11] and has been translated into German [12], Dutch [13], and Japanese [14]. The original English ETDQ-7 was translated into Arabic by 2 independent native Arabic doctors with excellent knowledge of the English language. The Arabic version was then translated again into English by 2 independent native English doctors with excellent knowledge of Arabic; the authors compared the back-translated version from Arabic to English with the original English version, and all differences were reconciled. This process was followed to make all aspects abundantly clear to readers.

To avoid recall bias, the participants were instructed to answer the questions of the ETDQ-7 based on the symptoms they had experienced in the past month [11]. The ETDQ-7 is a self-administered survey; yet, when needed, children received help from their parents to clarify and answer the questionnaire.

Statistical Analysis

The data were organized in an Excel sheet and transferred to Statistical Package for Social Sciences (SPSS) software (version 24; IBM Corp.) for further analysis. Categorical variables were described using a frequency table, whereas continuous variables were described using the mean and SD. The data were then processed for determining statistical significance using the Chi-square test. For all statistical tests, P values<.05 were considered significant.

A total of 2372 participants agreed to contribute to our study, resulting in a response rate of 78.00% (2372/3041). The study population comprised 64.71% (1534/2732) female and 35.28% (837/2732) male participants, with a mean age of 31.31 (SD 11.85) years. The largest age group comprised 45.06% (1070/2372) of our total sample and included participants aged 19-29 years. Data on the past medical history of our sample showed that only 3.37% (80/2372) and 5.52% (130/2372) of the participants had been diagnosed with ETD and hearing loss, respectively. Among the total sample, 37.48% (889/2372) reported a positive family history of hearing loss. Other demographic characteristics of the population are presented in Table 1.

The results of our analysis of the participants’ responses to the ETDQ-7 demonstrated that the overall prevalence of ETD in our sample was 42.49% (1008/2372). The fourth question—regarding “the presence of ear symptoms when having a cold or sinusitis”—recorded the highest mean score of the entire questionnaire. The mean scores of all the questions in the ETDQ-7 are shown in Table 1.

Table 1. Demographic characteristics of the sample and mean results of the ETDQ-7 (N=2372).

Age, mean (SD)31.31 (11.85)

Age groups (years), n (%)

≤18181 (7.63)

19-291069 (45.06)

30-39486 (20.48)

≥40636 (26.81)
Sex, n (%)

Male837 (35.28)

Female1535 (64.71)

Nationality, n (%)

Saudi2137 (90.09)

Non-Saudi235 (9.90)

Diagnosed with ETDa, n (%)

Yes80 (3.37)

No2292 (96.62)

Diagnosed with hearing loss, n (%)

Yes131 (5.52)

No2241 (94.47)

Family history of hearing loss, n (%)

Yes889 (37.47)

No1483 (62.52)

Smoking, n (%)

Yes332 (13.99)

No2040 (86.00)
Overall prevalence of ETD according to the ETDQ-7b, n (%)1008 (42.49)

Questions, mean (SD)

1- Pressure in the ears?1.961 (1.44)

2- Pain in the ears?2.046 (1.47)

3- A feeling that your ears are clogged or ‘under water’?2.280 (1.68)

4- Ear symptoms when you have a cold or sinusitis?2.417 (1.81)

5- Crackling or popping sounds in the ears?1.972 (1.59)

6- Ringing in the ears?2.066 (1. 62)

7- A feeling that your hearing is muffled?2.172 (1.72)

aETD: Eustachian tube dysfunction.

bETDQ-7: 7-question Eustachian tube dysfunction questionnaire.

Upon comparison of the prevalence of ETD on the basis of the demographic and clinical features of our sample, the condition was found to be most prevalent among participants aged 18 years or younger (45.3%), and its prevalence was similar in the groups aged 19-29 and 30-39 years (41.8% and 41.2%, respectively). In this study sample, ETD was more prevalent among females compared to males and among Saudi participants compared to non-Saudi participants. The prevalence of ETD was significantly higher among participants who had reported a previous diagnosis of ETD and hearing loss (1897/2372, 80% and 1902/2372, 80.2%, respectively; P<.001) than among participants with no history of such diagnoses. Additionally, participants with a family history of hearing loss had a significantly higher prevalence of ETD (1136/2372, 47.9; P<.001) than those with a negative family history. Details of the prevalence of ETD in the sample are presented in Table 2.

Multivariate regression revealed that a diagnosis of hearing loss, family history of hearing loss, diagnosis of ETD, gender, and smoking were associated with the prevalence of ETD. These data are presented in Table 3.

Table 2. Prevalence of ETD according to the ETDQ-7 (N=2372).
VariablesETDaP valueb
Age groups (years), n (%).65

≤1882 (45.30)

19-29447 (41.81)

30-39200 (41.23)

≥40279 (43.92)
Sex, n(%).01

Male326 (38.91)

Female682 (44.39)
Nationality, n (%).61

Saudi904 (42.30)

Non-Saudi104 (44.34)
Diagnosed with ETD,n (%)<.001

Yes64 (80.00)

No944 (41.23)
Diagnosed with hearing loss,n (%)<.001

Yes105 (80.21)

No903 (40.33)
Family history of hearing loss,n (%)<.001

Yes426 (47.92)

No582 (39.22)
Smoking,n (%).17

Yes153 (46.09)

No855 (41.91)

aETD: Eustachian tube dysfunction.

bP values were derived via the Chi-square test.

Table 3. Prevalence of ETD according to the ETDQ-7, based on multivariate analyses (N=2372).
VariablesRConfidence intervalP value
Diagnosed with hearing loss0.3490.263 to 0.436<.001
Diagnosed with ETDa0.3080.199 to 0.417<.001
Family history of hearing loss0.0630.023 to 0.103.002
Gender–0.073–0.117 to –0.030.001
Smoking0.064–0.004 to 0.124.04

aETD: Eustachian tube dysfunction.

The aim of this study was to estimate the prevalence of ETD among the public in Saudi Arabia—which, to our knowledge, has not been measured before—using the ETDQ-7 instrument. ETD negatively affects the outcomes of middle ear surgery and is highly associated with OME and cholesteatoma [15]. Multiple studies have shown that patients with other diseases such as temporomandibular joint dysfunctions also have tinnitus, vertigo, hypersensitivity to sounds, and hearing loss, but no recent studies have focused on using a specific tool to assess the general population [16-18]. Knowledge of the prevalence and risk factors of ETD will help improve the treatment options for patients and provide a better understanding of the condition with regard to a particular population. The overall prevalence of ETD in our sample was 42.49% (1008/2372), with the presence of “ear symptoms when having a cold or sinusitis” reported most frequently. Although this prevalence rate can be considered high, it is difficult to make a definitive judgement in this regard since there are no recent studies on the prevalence of ETD among general populations. Moreover, the ETDQ-7 has a score range of 7-49, and since any score above 14.5 was considered abnormal, the narrow range of scores might have led to a high number of diagnosed cases of ETD. Note that the estimated prevalence of ETD in the UK population is 0.9%, which was described by that study’s authors as a “common” condition [4].

In this study, a family history of hearing loss was significantly correlated with the presence of ETD (P<.001). Thus, family history played a major role in ETD prevalence in our study. Similarly, family history of OM has previously been suggested as a genetic factor for the development of OM [19-21]. We believe that the same factors might have contributed to the high prevalence of ETD in our study. Moreover, since families live together and share the same lifestyle habits, they are equally vulnerable to the same environmental risk factors of hearing loss.

Among participants below the age of 18 years, 45% (1067/2372) were diagnosed with ETD, making them the age group with the highest prevalence of ETD in this study. This finding is similar to that of a German study, which found that least 40% of all German children are affected by ETD [5]. The other age groups in our study exhibited similar prevalence rates of ETD. This might be partly attributed to the fact that the city of Jeddah is very crowded. It is the second largest city in Saudi Arabia, with an estimated population of around 4.03 million [22]. The city has significant industrial capabilities and is highly developed. The high population density and industrial environment of the city might serve as a major risk factor for ETD.

An unexpected finding was that females were at a greater risk of developing ETD than males (P=.01). A previous large-scale study reported that women above the age of 20 years are at a greater risk of developing ETD/OME/tympanic membrane retraction than men in the same age group [8]. The social lifestyles of men and women are different in Saudi Arabia, which might lead to the differences in the risk factors between the two sexes. Currently, we are unable to explain the reason behind this finding in our study, and thus, further research on the differences in lifestyle-based risk factors between the two sexes is needed.

Multiple recent diagnostic evaluations have helped improve the understanding of the human anatomy; examples include the dynamic functions of the eustachian tube orifice via simple nasal endoscopy and other research-related diagnostic tests such as sonotubometry, tubomanometry, the pressure chamber test, and inflation deflation test [23-30]. Bearing this in mind, ETD is diagnosed when symptoms of pressure disequilibrium exist in either ear, particularly with symptoms of aural fullness, popping, or discomfort/pain [31]. To our knowledge, no previous study has used the ETDQ-7 to measure the prevalence of ETD; however, since this study is the first to do so, our findings, which show a high prevalence of ETD (up to 40%) in the community, might indicate an overdiagnosis. Although the questionnaire was validated, it has not been previously used in a study following a methodology similar to ours; moreover, the authors who validated the questionnaire mentioned that their work was limited by the small sample size [11]. Additionally, one of the questions in the ETDQ-7 asked if the individual experiences ear symptoms when they have a cold or sinusitis, to which many of the participants gave a score of 7. This question might have misled the participants and thus affected the prevalence rates in our study, suggesting that this question might need to be more specific. Thus, if the ETDQ-7 is to be used as a tool to assess the prevalence of ETD in a clinical sitting, the abovementioned question might affect its overall sensitivity considerably; indeed, this observation was also made by similar studies [32,33].

A major limitation of this research related to our inability to include people of all socioeconomic sections of society in Jeddah or ensure that our study covered all residential regions of the city. Future studies should consider different environmental risk factors when collecting data and attempt to identify an association between hearing loss and ETD. They should also evaluate the prevalence of ETD in all regions and neighborhoods of the city and consider the extent of noise exposure in each region. Another suggestion for future investigations would be to analyze the prevalence of ETD among vulnerable population groups such as those exposed to occupational and environmental risk factors. Our study design can be applied to larger studies on a national or an international scale, which will help compare the prevalence of ETD among different cultures and identify more specific risk factors for the condition. Given the high prevalence of ETD in our study, more research and awareness on ETD in the community are needed.

In conclusion, this study aimed to determine the prevalence of ETD among the public in Saudi Arabia by using the ETDQ-7. Our results showed that ETD is a common disease in Jeddah. The prevalence of ETD was significantly higher among participants who had reported a previous diagnosis of ETD and hearing loss. Therefore, this condition needs more attention, awareness, and research (particularly the use of advanced statistical analysis). In addition, since smoking has a significant impact on ETD and tends to cluster in families, the potential role of smoking in family history of ETD should be examined.


We are grateful to Shahad Ali Aleiidi, Ahmed Habib Alshaikh, Ohoud Muqbil Almutairi, Sultan Sameer Alrabghi, and Meshal ldhubabian for participating in the data collection for this research. We would also like to acknowledge Mohammed Al-Shmrani for reviewing the statistical analysis.

Authors' Contributions

All authors contributed equally during the preparation of this paper. The final proofreading of the manuscript was completed by KA.

Conflicts of Interest

None declared.

  1. Bluestone C. Eustachian Tube: Structure, Function, Role in Otitis Media. Raleigh, Nc: People's Medical Publishing House-USA; 2005.
  2. McCoul ED, Anand VK. Eustachian tube balloon dilation surgery. Int Forum Allergy Rhinol 2012;2(3):191-198. [CrossRef] [Medline]
  3. Swarts J, Bluestone CD. Eustachian tube function in older children and adults with persistent otitis media. Int J Pediatr Otorhinolaryngol 2003 Aug;67(8):853-859. [CrossRef] [Medline]
  4. Browning GG, Gatehouse S. The prevalence of middle ear disease in the adult British population. Clin Otolaryngol 1992;17(4):317-321. [CrossRef]
  5. Martino E, Di Thaden R, Krombach G, Westhofen M. [Function tests for the Eustachian tube. Current knowledge]. HNO 2004 Nov;52(11):1029-39; quiz 1040. [CrossRef] [Medline]
  6. Todd NW. There are no accurate tests for Eustachian tube function. Arch Otolaryngol Head Neck Surg 2000 Aug 01;126(8):1041. [CrossRef]
  7. Choi SH, Han JH, Chung JW. Pre-operative evaluation of Eustachian tube function using a modified pressure equilibration test is predictive of good postoperative hearing and middle ear aeration in type 1 tympanoplasty patients. Clin Exp Otorhinolaryngol 2009 Jun;2(2):61-65 [FREE Full text] [CrossRef] [Medline]
  8. Vila PM, Thomas T, Liu C, Poe D, Shin JJ. The burden and epidemiology of Eustachian tube dysfunction in adults. Otolaryngol Head Neck Surg 2017 Feb 24;156(2):278-284. [CrossRef] [Medline]
  9. Furukawa C. Conductive hearing loss and speech development. J Allergy Clin Immunol 1988 May;81(5 Pt 2):1015-1020. [CrossRef] [Medline]
  10. Teixeira MS, Swarts JD, Alper CM. Accuracy of the ETDQ-7 for identifying persons with Eustachian tube dysfunction. Otolaryngol Head Neck Surg 2018 Jan 26;158(1):83-89 [FREE Full text] [CrossRef] [Medline]
  11. McCoul ED, Anand VK, Christos PJ. Validating the clinical assessment of eustachian tube dysfunction: The Eustachian Tube Dysfunction Questionnaire (ETDQ-7). Laryngoscope 2012 May 28;122(5):1137-1141 [FREE Full text] [CrossRef] [Medline]
  12. Schröder S, Lehmann M, Sudhoff H, Ebmeyer J. [Assessment of chronic obstructive eustachian tube dysfunction : Evaluation of the German version of the Eustachian Tube Dysfunction Questionnaire]. HNO 2014 Mar 24;62(3):160, 162-160, 164. [CrossRef] [Medline]
  13. Van Roeyen S, Van de Heyning P, Van Rompaey V. Value and discriminative power of the seven-item Eustachian Tube Dysfunction Questionnaire. Laryngoscope 2015 Nov 17;125(11):2553-2556. [CrossRef] [Medline]
  14. Ikeda R, Kikuchi T, Miyazaki H, Hidaka H, Kawase T, Katori Y, et al. The efficacy of the Eustachian Tube Dysfunction Questionnaire (ETDQ-7) for patulous Eustachian tube patient. Acta Otolaryngol 2018 Jan 07;138(1):6-9. [CrossRef] [Medline]
  15. Norman G, Llewellyn A, Harden M, Coatesworth A, Kimberling D, Schilder A, et al. Systematic review of the limited evidence base for treatments of Eustachian tube dysfunction: a health technology assessment. Clin Otolaryngol 2014 Mar;39(1):6-21. [CrossRef] [Medline]
  16. Ferendiuk E, Zajdel K, Pihut M. Incidence of otolaryngological symptoms in patients with temporomandibular joint dysfunctions. In: Biomed Res Int. Pihut M: Incidence of otolaryngological symptoms in patients with temporomandibular joint dysfunctions. Biomed Res Int 2014; 2014:824684.
  17. Tuz HH, Onder EM, Kisnisci RS. Prevalence of otologic complaints in patients with temporomandibular disorder. Am J Orthod Dentofacial Orthop 2003 Jun;123(6):620-623. [CrossRef] [Medline]
  18. Maciejewska-Szaniec Z, Maciejewska B, Mehr K. The otological symptoms among patients with the temporomandibular disorders. Forum Med Rodz 2015;2:87.
  19. Casselbrant ML, Mandel EM, Fall PA, Rockette HE, Kurs-Lasky M, Bluestone CD, et al. The heritability of otitis media: a twin and triplet study. JAMA 1999 Dec 08;282(22):2125-2130. [CrossRef] [Medline]
  20. Kvestad E, Kvaerner KJ, Røysamb E, Tambs K, Harris JR, Magnus P. Otitis media: genetic factors and sex differences. Twin Res 2004 Jun 01;7(3):239-244. [CrossRef] [Medline]
  21. Rovers M, Haggard M, Gannon M, Koeppen-Schomerus G, Plomin R. Heritability of symptom domains in otitis media: a longitudinal study of 1,373 twin pairs. Am J Epidemiol 2002 May 15;155(10):958-964. [CrossRef] [Medline]
  22. Ahmad I, Rehan M, Balkhyour M, Abbas M, Basahi J, Almeelbi T. Review of environmental pollution and health risks at motor vehicle repair workshops: Challenges and perspectives for Saudi Arabia. Int J Agric Environ Res 2016;2(1):1-23.
  23. Poe DS, Pyykkö I. Measurements of Eustachian tube dilation by video endoscopy. Otol Neurotol 2011 Jul;32(5):794-798. [CrossRef] [Medline]
  24. Alper CM, Teixeira MS, Swarts JD, Doyle WJ. Quantitative description of eustachian tube movements during swallowing as visualized by transnasal videoendoscopy. JAMA Otolaryngol Head Neck Surg 2015 Mar 01;141(2):160-168. [CrossRef] [Medline]
  25. Virtanen H. Sonotubometry. An acoustical method for objective measurement of auditory tubal opening. Acta Otolaryngol 1978;86(1-2):93-103. [CrossRef] [Medline]
  26. Asenov DR, Nath V, Telle A, Antweiler C, Walther LE, Vary P, et al. Sonotubometry with perfect sequences: First results in pathological ears. Acta Otolaryngol 2010 Nov 16;130(11):1242-1248. [CrossRef] [Medline]
  27. Teixeira MS, Banks J, Swarts JD, Alper CM, Doyle WJ. Eustachian tube opening measured by sonotubometry is poorer in adults with a history of past middle ear disease. Int J Pediatr Otorhinolaryngol 2014 Apr;78(4):593-598 [FREE Full text] [CrossRef] [Medline]
  28. Doyle WJ, Swarts JD, Banks J, Casselbrant ML, Mandel EM, Alper CM. Sensitivity and specificity of eustachian tube function tests in adults. JAMA Otolaryngol Head Neck Surg 2013 Jul 01;139(7):719-727 [FREE Full text] [CrossRef] [Medline]
  29. Alper CM, Teixeira MS, Kim JH, Douglas Swarts J. Diagnostic accuracy of tubomanometry R value in detecting the Eustachian tube pressure equalizing function. Eur Arch Otorhinolaryngol 2017 Apr 21;274(4):1865-1872. [CrossRef] [Medline]
  30. Smith M, Tysome J. Tests of Eustachian tube function: a review. Clin Otolaryngol 2015 Aug 15;40(4):300-311. [CrossRef] [Medline]
  31. Schilder A, Bhutta M, Butler C, Holy C, Levine L, Kvaerner K, et al. Eustachian tube dysfunction: consensus statement on definition, types, clinical presentation and diagnosis. Clin Otolaryngol 2015 Oct 07;40(5):407-411 [FREE Full text] [CrossRef] [Medline]
  32. Newman AC, Omrani K, Higgins TS, Ting JY, Walgama ES, Wu AW. The prevalence of eustachian tube dysfunction symptoms in temporomandibular joint disorder patients. Laryngoscope 2020 Apr;130(4):E233-E236. [CrossRef] [Medline]
  33. Tangbumrungtham N, Patel VS, Thamboo A, Patel ZM, Nayak JV, Ma Y, et al. The prevalence of Eustachian tube dysfunction symptoms in patients with chronic rhinosinusitis. Int Forum Allergy Rhinol 2018 May 11;8(5):620-623. [CrossRef] [Medline]

ETD: Eustachian tube dysfunction
ETDQ-7: 7-item Eustachian Tube Dysfunction Questionnaire
OM: Otitis media
OME: Otitis media with effusion

Edited by G Eysenbach; submitted 07.05.19; peer-reviewed by Y Shu, O Handzel, Y Chu, P Naik; comments to author 14.12.19; revised version received 29.02.20; accepted 03.09.20; published 19.11.20


©Khalid A Alshehri, Omar M Saggaf, Hussein M Alshamrani, Abdulrahman Mutlaq Alnefaie, Khalid B Alghamdi. Originally published in the Interactive Journal of Medical Research (, 19.11.2020.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Interactive Journal of Medical Research, is properly cited. The complete bibliographic information, a link to the original publication on, as well as this copyright and license information must be included.