<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "journalpublishing.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="2.0" xml:lang="en" article-type="review-article"><front><journal-meta><journal-id journal-id-type="nlm-ta">Interact J Med Res</journal-id><journal-id journal-id-type="publisher-id">i-jmr</journal-id><journal-id journal-id-type="index">3</journal-id><journal-title>Interactive Journal of Medical Research</journal-title><abbrev-journal-title>Interact J Med Res</abbrev-journal-title><issn pub-type="epub">1929-073X</issn><publisher><publisher-name>JMIR Publications</publisher-name><publisher-loc>Toronto, Canada</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">v14i1e72231</article-id><article-id pub-id-type="doi">10.2196/72231</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Digital Interventions for Improving Body Dissatisfaction in Children and Emerging Adults: Systematic Review and Meta-Analysis</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Liu</surname><given-names>Li</given-names></name><degrees>BSc</degrees><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Yang</surname><given-names>Jianning</given-names></name><degrees>MEng</degrees><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Tan</surname><given-names>Fengmei</given-names></name><degrees>MSN</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Yang</surname><given-names>Xia</given-names></name><degrees>BSN</degrees><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Luo</surname><given-names>Huan</given-names></name><degrees>BSN</degrees><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name name-style="western"><surname>Chen</surname><given-names>Yanhua</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author" corresp="yes"><name name-style="western"><surname>Zhao</surname><given-names>Xiaolei</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1">1</xref></contrib></contrib-group><aff id="aff1"><institution>School of Nursing, Southwest Medical University</institution><addr-line>1 Xianglin Road, Longmatan District</addr-line><addr-line>Luzhou</addr-line><addr-line>Sichuan</addr-line><country>China</country></aff><aff id="aff2"><institution>Department of Hematopathology, The Affiliated Hospital, Southwest Medical University</institution><addr-line>Luzhou</addr-line><addr-line>Sichuan</addr-line><country>China</country></aff><aff id="aff3"><institution>Department of Nephrology, The Affiliated Hospital, Southwest Medical University</institution><addr-line>Luzhou</addr-line><addr-line>Sichuan</addr-line><country>China</country></aff><aff id="aff4"><institution>Department of Nursing, The Affiliated Hospital, Southwest Medical University</institution><addr-line>Luzhou</addr-line><addr-line>Sichuan</addr-line><country>China</country></aff><contrib-group><contrib contrib-type="editor"><name name-style="western"><surname>Cardoso</surname><given-names>Taiane de Azevedo</given-names></name></contrib></contrib-group><contrib-group><contrib contrib-type="reviewer"><name name-style="western"><surname>Goel</surname><given-names>Neha J</given-names></name></contrib><contrib contrib-type="reviewer"><name name-style="western"><surname>Shi</surname><given-names>Peng</given-names></name></contrib></contrib-group><author-notes><corresp>Correspondence to  Xiaolei Zhao, PhD, School of Nursing, Southwest Medical University, 1 Xianglin Road, Longmatan District, Luzhou, Sichuan, 646000, China, 86 13980250224; <email>zhaoxiaolei8866@163.com</email></corresp></author-notes><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>13</day><month>8</month><year>2025</year></pub-date><volume>14</volume><elocation-id>e72231</elocation-id><history><date date-type="received"><day>06</day><month>02</month><year>2025</year></date><date date-type="rev-recd"><day>22</day><month>06</month><year>2025</year></date><date date-type="accepted"><day>23</day><month>06</month><year>2025</year></date></history><copyright-statement>&#x00A9; Li Liu, Jianning Yang, Fengmei Tan, Xia Yang, Huan Luo, Yanhua Chen, Xiaolei Zhao. Originally published in the Interactive Journal of Medical Research (<ext-link ext-link-type="uri" xlink:href="https://www.i-jmr.org/">https://www.i-jmr.org/</ext-link>), 13.8.2025. </copyright-statement><copyright-year>2025</copyright-year><license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/"><p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (<ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link>), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Interactive Journal of Medical Research, is properly cited. The complete bibliographic information, a link to the original publication on <ext-link ext-link-type="uri" xlink:href="https://www.i-jmr.org/">https://www.i-jmr.org/</ext-link>, as well as this copyright and license information must be included.</p></license><self-uri xlink:type="simple" xlink:href="https://www.i-jmr.org/2025/1/e72231"/><abstract><sec><title>Background</title><p>Body dissatisfaction is a condition where individuals are dissatisfied with their physical appearance. It has become a global issue, especially among children and emerging adults. A growing number of digital interventions have been developed to address body dissatisfaction in children and emerging adults; however, controversies remain regarding their efficacy, underscoring the need for a comprehensive synthesis of current evidence.</p></sec><sec><title>Objective</title><p>This systematic review aimed to explore the effectiveness of digital interventions in improving body image&#x2013;related outcomes among children and emerging adults.</p></sec><sec sec-type="methods"><title>Methods</title><p>From inception to April 24, 2024, a literature search was performed across 7 databases&#x2014;PubMed, Web of Science, MEDLINE, EBSCO (Elton B Stephens Company), Cochrane Library, CNKI (China National Knowledge Infrastructure), and WANFANG&#x2014;to identify randomized controlled trials (RCTs) with a predefined set of inclusion criteria. This systematic review was reported in line with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. Study selection, data extraction, and risk of bias assessment using the Cochrane Risk-of-Bias Tool 2.0 were conducted independently by 2 researchers. Standardized mean differences (SMDs) and 95% CIs from the included RCTs were calculated for the meta-analysis. Heterogeneity was assessed with <italic>I</italic>&#x00B2; values. A fixed-effects model was used when <italic>I</italic>&#x00B2;&#x2264;50%, and a random-effects model was selected when <italic>I</italic>&#x00B2;&#x003E;50%.</p></sec><sec sec-type="results"><title>Results</title><p>Twenty RCTs with 5251 participants (2610 in intervention groups and 2641 in control groups) met the inclusion criteria. Digital interventions included web pages, mobile apps, computer-based videos, computer-based sessions, internet-based sessions, internet games, chatbots, podcasts, and social media. Our results indicate that digital interventions could significantly improve body dissatisfaction (SMD=0.38, 95% CI &#x2212;0.63 to &#x2212;0.13; <italic>I</italic><sup>2</sup>=55%; <italic>P</italic>=.003), physical appearance comparison (SMD=&#x2212;0.24, 95% CI &#x2212;0.45 to &#x2212;0.03; <italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.003), thin-ideal internalization (SMD=&#x2212;0.28, 95% CI &#x2212;0.36 to &#x2212;0.2; <italic>I</italic><sup>2</sup>=41%; <italic>P</italic>&#x003C;.001), self-esteem (SMD=0.14, 95% CI 0.07-0.21; <italic>I</italic><sup>2</sup>=21%; <italic>P</italic>&#x003C;.001), self-compassion (SMD=0.55, 95% CI 0.33-0.78; <italic>I<sup>2</sup></italic>=35%; <italic>P</italic>&#x003C;.001), and depression (SMD=&#x2212;0.59, 95% CI &#x2212;0.97 to &#x2212;0.21; <italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.002), with small to medium effect sizes.</p></sec><sec sec-type="conclusions"><title>Conclusions</title><p>While digital interventions improved body dissatisfaction among children and emerging adults, additional well-designed, rigorous, and large-scale RCTs are needed to decisively provide estimates of the effectiveness of digital interventions on body dissatisfaction.</p></sec><sec><title>Trial Registration</title><p>PROSPERO CRD42024567594; https://www.crd.york.ac.uk/PROSPERO/view/CRD42024567594</p></sec></abstract><kwd-group><kwd>body dissatisfaction</kwd><kwd>digital intervention</kwd><kwd>children</kwd><kwd>emerging adults</kwd><kwd>systematic review</kwd><kwd>meta-analysis</kwd><kwd>PRISMA</kwd></kwd-group></article-meta></front><body><sec id="s1" sec-type="intro"><title>Introduction</title><sec id="s1-1"><title>Prevalence and Impacts of Body Dissatisfaction</title><p>Body image encompasses an individual&#x2019;s cognition, emotional attitudes, and behavioral regulation regarding their body, and is a multidimensional concept [<xref ref-type="bibr" rid="ref1">1</xref>]. Dissatisfaction with one&#x2019;s body&#x2019;s appearance, including its shape, weight, and other features, is known as body dissatisfaction [<xref ref-type="bibr" rid="ref2">2</xref>]. Body dissatisfaction has a pervasive hold on children and emerging adults, and the phenomenon has been described as &#x201C;normative discontent&#x201D; [<xref ref-type="bibr" rid="ref3">3</xref>]. Studies showed the prevalence of body dissatisfaction ranged from 42.2% to 80.9% among children and emerging adults across the world [<xref ref-type="bibr" rid="ref4">4</xref>-<xref ref-type="bibr" rid="ref7">7</xref>]. Females, those with higher BMI, and those from minority groups were reported to experience greater body dissatisfaction [<xref ref-type="bibr" rid="ref8">8</xref>]. Body dissatisfaction can lead to a range of physiological issues, such as low self-esteem [<xref ref-type="bibr" rid="ref9">9</xref>], anxiety [<xref ref-type="bibr" rid="ref10">10</xref>], and depression [<xref ref-type="bibr" rid="ref11">11</xref>], as well as behavioral burdens, such as eating disorders [<xref ref-type="bibr" rid="ref12">12</xref>], extreme weight loss behaviors [<xref ref-type="bibr" rid="ref13">13</xref>], alcohol, drug abuse [<xref ref-type="bibr" rid="ref14">14</xref>], and excessive pursuit of cosmetic procedures [<xref ref-type="bibr" rid="ref15">15</xref>]. The direct economic costs of body dissatisfaction were estimated to be US $84 billion in the United States [<xref ref-type="bibr" rid="ref16">16</xref>].</p></sec><sec id="s1-2"><title>Existing Face-to-Face Interventions and Limitations</title><p>Existing face-to-face interventions, such as cognitive behavioral therapy (CBT) and behavior interventions and supports (BIS), demonstrated small to moderate efficacy in reducing body dissatisfaction. For instance, CBT helps reframe maladaptive thoughts about body image [<xref ref-type="bibr" rid="ref17">17</xref>], while dissonance-based interventions like the EVERYbody Project reduced thin-ideal internalization and eating disorder symptoms in college students [<xref ref-type="bibr" rid="ref18">18</xref>]. A systematic review revealed that behavior interventions and supports improved disordered eating, body dissatisfaction, and extreme weight control behaviors in girls, but not boys [<xref ref-type="bibr" rid="ref19">19</xref>]. However, the face-to-face interventions are sometimes constrained by accessibility, the costly nature of the format, a global shortage of mental health professionals, or stigma [<xref ref-type="bibr" rid="ref20">20</xref>].</p></sec><sec id="s1-3"><title>Efficacy of Digital Interventions</title><p>Digital technologies offered cost-effective alternatives in body dissatisfaction interventions [<xref ref-type="bibr" rid="ref21">21</xref>]. Although studies identified that social media engagement was associated with higher body dissatisfaction and restricting food [<xref ref-type="bibr" rid="ref22">22</xref>], digital interventions could offer especially critical support in adolescents [<xref ref-type="bibr" rid="ref23">23</xref>]. A systematic review assessed the effectiveness of universal body image interventions delivered through a digital platform among young women. Most articles indicated that these interventions were effective in improving at least one body image outcome [<xref ref-type="bibr" rid="ref24">24</xref>]. However, findings in other studies remained inconsistent. A study involving 127 girls aged 10-13 years, using videos developed by the Dove Self-Esteem Project, revealed that after intervention, there was no significant difference between the intervention group and the control group on body satisfaction [<xref ref-type="bibr" rid="ref25">25</xref>]. This highlights the need for a comprehensive synthesis of current evidence.</p></sec><sec id="s1-4"><title>Gaps in Current Evidence</title><p>There was no systematic review to explore the effectiveness of digital interventions on body dissatisfaction in children and emerging adults through quantitative synthesis. In this regard, this study aimed to fill this identified gap in the literature through a meta-analysis and to synthesize the effectiveness of various digital interventions on children and emerging adults with body dissatisfaction. By providing meta-analyses of currently available randomized controlled trials in children and emerging adults, this paper aimed to consolidate evidence on the use of digital interventions to treat body dissatisfaction.</p></sec></sec><sec id="s2" sec-type="methods"><title>Methods</title><sec id="s2-1"><title>Search Strategy</title><p>This systematic review was reported in line with PRISMA (Preferred Reporting Items for Systematic Review and Meta-analysis) guidelines [<xref ref-type="bibr" rid="ref26">26</xref>] (the PRISMA checklist is provided in <xref ref-type="supplementary-material" rid="app11">Checklist 1</xref>). PubMed, Web of Science, MEDLINE, EBSCO (Elton B Stephens Company), Cochrane Library, the Chinese databases CNKI (China National Knowledge Infrastructure) and WANFANG were searched from inception to April 24, 2024. This process was carried out independently by 2 researchers (LL &#x0026; JNY). The PICOS (population, intervention, comparison, outcome, and study design) formula was used:</p><list list-type="bullet"><list-item><p>Population (#1): youth OR young* OR child* OR adolescent OR teen* OR juvenile OR junior OR girl OR boy OR adult or students;</p></list-item><list-item><p>Intervention (#2): remote OR website OR digital OR online OR network OR phone OR internet OR eHealth OR mHealth OR app OR multimedia OR social media OR zoom OR Facebook OR Instagram OR telephone OR (virtual reality);</p></list-item><list-item><p>Comparison (#3): &#x201C;usual care&#x201D;;</p></list-item><list-item><p>Outcomes (#4): (body image) OR (body shape) OR (body dissatisfaction) OR (body weight) OR (physical appearance);</p></list-item><list-item><p>Study design (#5): randomized controlled trials.</p></list-item></list><p>The final search strategy is #1 AND #2 AND #3, with #4 (Type of Study: randomized controlled trial) applied as a filter. Reference lists of publications were also searched for potentially relevant studies (see <xref ref-type="supplementary-material" rid="app1">Multimedia Appendix 1</xref>).</p></sec><sec id="s2-2"><title>Inclusion and Exclusion Criteria</title><sec id="s2-2-1"><title>Design</title><p>Any randomized controlled trial (RCT) in English or Chinese that explored the effects of digital interventions on body dissatisfaction among children or emerging adults was included, including randomized waitlist-controlled trials and crossover RCTs.</p></sec><sec id="s2-2-2"><title>Participants</title><p>Children (&#x003C;18 years [<xref ref-type="bibr" rid="ref27">27</xref>]) or emerging adults (18&#x2010;25 years [<xref ref-type="bibr" rid="ref28">28</xref>]) with body dissatisfaction were included. Some special groups of children or emerging adults were excluded, including but not limited to those who were pregnant, postpartum women, new mothers, children, or emerging adults with amputation, patients with cancer, models, or cosmetic surgery sequelae. Only children&#x2019;s data were extracted if parents and children had been involved in the RCTs as participants.</p></sec><sec id="s2-2-3"><title>Intervention</title><p>Intervention methods were based on Internet or smartphone technologies, including apps, web pages, virtual reality, telemedicine, Zoom (Zoom Video Communications), Facebook (Meta Platforms), Instagram (Meta Platforms), and other social media.</p></sec><sec id="s2-2-4"><title>Outcomes</title><p>Outcomes of interest include at least one of the following measures, primary outcomes: body image satisfaction or dissatisfaction, such as body dissatisfaction, body appreciation, shape and weight concerns, and physical appearance comparisons; secondary outcomes: internalized outcomes, such as self-esteem, self-compassion, thin-ideal internalization, and self-objectification; negative affect, such as depression and anxiety symptoms, and negative affect; and eating behaviors, such as eating disorder and eating restraint. These secondary outcomes were selected based on the Tripartite Influence Model [<xref ref-type="bibr" rid="ref29">29</xref>], which presents that family, peers, and media influence an individual&#x2019;s body dissatisfaction via appearance-related social comparisons and thin-ideal internalization. Thin-ideal internalization serves as a predictor of body dissatisfaction [<xref ref-type="bibr" rid="ref30">30</xref>], while studies showed that body dissatisfaction acted as a risk factor for negative affect [<xref ref-type="bibr" rid="ref31">31</xref>] and eating disorder pathology [<xref ref-type="bibr" rid="ref32">32</xref>].</p></sec><sec id="s2-2-5"><title>Study Selection</title><p>The reference manager EndNote 21 (Clarivate) was used to manage studies and remove duplicates. The remaining records were screened by 2 independent reviewers (LL and JNY) based on the titles and the abstracts. The full text of studies that either reviewer identified as potentially eligible continued to be read and screened by the 2 independent reviewers (LL and JNY) based on the inclusion and exclusion criteria. Any discrepancies were resolved with the third reviewer (XLZ) until consensus was reached.</p></sec><sec id="s2-2-6"><title>Quality Assessment</title><p>The risk of bias in eligible RCTs was independently assessed by the 2 reviewers (LL and JNY) according to 7 domains of the Cochrane risk-of-bias tool for randomized trials [<xref ref-type="bibr" rid="ref33">33</xref>]: (1) random sequence generation, (2) allocation concealment, (3) blinding of participants and personnel, (4) blinding of outcome assessment, (5) incomplete outcome data, (6) selective reporting, and (7) other potential sources of bias. For each domain, the risk of bias was classified as low, high, or unclear. Discrepancies were adjudicated by the third reviewer (XLZ) until a consensus was achieved. Studies were considered low risk of bias if all 7 domains were assessed as low risk, or only one domain was assessed as high risk or unclear. If 2 domains were assessed as high risk or unclear, the studies were determined to have some concerns. If more than 2 domains were assessed as high risk or unclear, the study was rated a high risk of bias [<xref ref-type="bibr" rid="ref34">34</xref>].</p></sec><sec id="s2-2-7"><title>Data Extraction</title><p>A standardized data extraction form was used to extract data from each study, which included the following details: (1) first author, the year of publication, and country; (2) inclusion and exclusion criteria; (3) sample size of the experimental and control groups; (4) intervention characteristics (contents of intervention and comparison, follow-up); and (5) outcomes and main results. Data were extracted by LL and JNY and verified by XLZ. Only the data in the first period were extracted in the randomized waitlist-controlled trials. Only the data in the digital intervention groups and the control groups were extracted when participants were divided into more than 2 groups.</p></sec><sec id="s2-2-8"><title>Data Analysis</title><p>Review Manager v5.4.1 (Cochrane Collaboration) was used for data synthesis. The findings that could not be synthesized were narratively described based on the outcomes of interest. For the continuous variables, standardized mean difference (SMD) and 95% CIs were calculated through random or fixed-effects models when the studies assessed the same outcome. SMD values of 0.2&#x2010;0.5 represented a small effect size, 0.5&#x2010;0.8 was considered medium, and values greater than 0.8 were interpreted as large [<xref ref-type="bibr" rid="ref35">35</xref>]. The effect size of individual studies was mainly combined using the random effects model because of the different scales involved in assessing the same outcomes. The <italic>I<sup>2</sup></italic> statistic was used to assess the heterogeneity across studies. <italic>I</italic><sup><italic>2</italic></sup> values of 25%, 50%, and 75% were considered as low, moderate, and high heterogeneity [<xref ref-type="bibr" rid="ref36">36</xref>]. When <italic>I</italic>&#x00B2;&#x2264;50%, a fixed-effects model was selected; otherwise, a random-effects model was used [<xref ref-type="bibr" rid="ref37">37</xref>]. Strategies for addressing heterogeneity included choosing a random or fixed effect model, excluding studies, or conducting subgroup analysis. The test level was <italic>&#x03B1;</italic>=.05, and <italic>P</italic>&#x003C;.05 was considered to indicate statistical significance.</p></sec></sec><sec id="s2-3"><title>Ethical Considerations</title><p>This systematic review is based on the synthesis of previously published studies and does not involve the collection of primary data directly from human participants. As such, formal ethical approval, including an institutional review board approval number, informed consent, and compensation, was not applicable. However, we have adhered to the ethical principles of research, including the accurate and transparent reporting of study findings. We have also ensured that all included studies were conducted in accordance with relevant ethical guidelines and regulations.</p></sec></sec><sec id="s3" sec-type="results"><title>Results</title><sec id="s3-1"><title>Search Results</title><p>A total of 808 records were identified from the initial literature search. After removing the duplicates, titles and abstracts were screened, and 42 studies were further reviewed in full text. Finally, 20 studies [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref56">56</xref>] met the inclusion criteria, including 9 [<xref ref-type="bibr" rid="ref41">41</xref>-<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref56">56</xref>] studies identified from reference lists. The study selection flow chart is shown in <xref ref-type="fig" rid="figure1">Figure 1</xref>.</p><fig position="float" id="figure1"><label>Figure 1.</label><caption><p>Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow diagram.</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="i-jmr_v14i1e72231_fig01.png"/></fig></sec><sec id="s3-2"><title>Study Characteristics</title><p>All the studies included were RCTs, including randomized waitlist-controlled trials (n=7). Only the data in the first phase were extracted in the randomized crossover and waitlist trials. Of the included studies, 20 RCTs with 5251 participants were included, including 2610 participants in the intervention groups and 2641 participants in the control groups. The studies were published between 2000 and 2023 and were conducted in the United States (n=10), Australia (n=3), the United Kingdom (n=3), China (n=1), Indonesia (n=1), Italy (n=1), and Brazil (n=1). Five studies [<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref42">42</xref>] had mixed-gender samples, 15 [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref56">56</xref>] with only females. Sample sizes of the included studies ranged from 53 to 2000. All studies reported postintervention effects, whereas short-term and long-term follow-up data were reported in 11 [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref51">51</xref>-<xref ref-type="bibr" rid="ref56">56</xref>] and 3 [<xref ref-type="bibr" rid="ref39">39</xref>-<xref ref-type="bibr" rid="ref41">41</xref>] studies, respectively. Participants and study characteristics are summarized in <xref ref-type="table" rid="table1">Table 1</xref>.</p><p>The digital interventions mainly included web page (n=6), computer-based sessions (n=1), internet-based sessions (n=2), computer-based videos (n=2), social media&#x2013;based video (n=1), social media (n=3), such as Facebook and podcasts, mobile apps (n=2), internet games (n=1), animated films (n=1), and chatbot (n=1). Among the included studies, the interventions varied in length from 1 minute to 2 hours per session and in duration, ranging from a single day up to 8 weeks.</p><table-wrap id="t1" position="float"><label>Table 1.</label><caption><p>Characteristics of the 20 included randomized controlled trials.</p></caption><table id="table1" frame="hsides" rules="groups"><thead><tr><td align="left" valign="bottom">Author (year, country)</td><td align="left" valign="bottom">Participants</td><td align="left" valign="bottom">Sample size</td><td align="left" valign="bottom">Intervention</td><td align="left" valign="bottom">Comparison</td><td align="left" valign="bottom">Follow-up</td><td align="left" valign="bottom">Outcomes</td></tr></thead><tbody><tr><td align="left" valign="top">Winzelberg et al,2000 (United States) [<xref ref-type="bibr" rid="ref43">43</xref>]</td><td align="left" valign="top">Female university students</td><td align="left" valign="top">T:<sup><xref ref-type="table-fn" rid="table1fn1">a</xref></sup> n=31, C:<sup><xref ref-type="table-fn" rid="table1fn2">b</xref></sup> n=29</td><td align="left" valign="top">Internet-based sessions</td><td align="left" valign="top">Waitlist control group</td><td align="left" valign="top">3 months</td><td align="left" valign="top">BSQ<sup><xref ref-type="table-fn" rid="table1fn3">c</xref></sup>, EDI-DT<sup><xref ref-type="table-fn" rid="table1fn4">d</xref></sup>, EDEQ<sup><xref ref-type="table-fn" rid="table1fn5">e</xref></sup>, WCSC<sup><xref ref-type="table-fn" rid="table1fn6">f</xref></sup></td></tr><tr><td align="left" valign="top">Bruning et al, 2004 (United States) [<xref ref-type="bibr" rid="ref44">44</xref>]</td><td align="left" valign="top">14&#x2010; to 16-year-old girls and their parents</td><td align="left" valign="top">T: n=102, C: n=51</td><td align="left" valign="top">Web page</td><td align="left" valign="top">Waitlist control group</td><td align="left" valign="top">6 months</td><td align="left" valign="top">WDEQ, WSCS<sup><xref ref-type="table-fn" rid="table1fn6">f</xref></sup>, EDI-DT</td></tr><tr><td align="left" valign="top">Low et al,<break/>2006<break/>(United States) [<xref ref-type="bibr" rid="ref45">45</xref>]</td><td align="left" valign="top">First- and second-year female undergraduates</td><td align="left" valign="top">T: n=14, C: n=14</td><td align="left" valign="top">Computer-Based sessions</td><td align="left" valign="top">No intervention</td><td align="left" valign="top">8 months</td><td align="left" valign="top">EDI<sup><xref ref-type="table-fn" rid="table1fn7">g</xref></sup>, SFRS<sup><xref ref-type="table-fn" rid="table1fn8">h</xref></sup>, EDI-DT, SATA<sup><xref ref-type="table-fn" rid="table1fn9">i</xref></sup></td></tr><tr><td align="left" valign="top">Heinicke et al, 2007<break/>(Australia) [<xref ref-type="bibr" rid="ref46">46</xref>]</td><td align="left" valign="top">12&#x2010; to 18-year-old females</td><td align="left" valign="top">T: n=36, C: n=37</td><td align="left" valign="top">Internet-based sessions</td><td align="left" valign="top">Waitlist control group</td><td align="left" valign="top">2 months,<break/>6 months</td><td align="left" valign="top">BSQ-SF<sup><xref ref-type="table-fn" rid="table1fn10">j</xref></sup>, BCS<sup><xref ref-type="table-fn" rid="table1fn11">k</xref></sup>, DEBQ<sup><xref ref-type="table-fn" rid="table1fn12">l</xref></sup>, SATA, BDI<sup><xref ref-type="table-fn" rid="table1fn13">m</xref></sup></td></tr><tr><td align="left" valign="top">Cousineau et al, 2010 (United States) [<xref ref-type="bibr" rid="ref38">38</xref>]</td><td align="left" valign="top">6th-grade students</td><td align="left" valign="top">T: n=92, C: n=98</td><td align="left" valign="top">Web page</td><td align="left" valign="top">Science-based websites</td><td align="left" valign="top">3 months</td><td align="left" valign="top">BESAA<sup><xref ref-type="table-fn" rid="table1fn14">n</xref></sup>, SPPA<sup><xref ref-type="table-fn" rid="table1fn15">o</xref></sup></td></tr><tr><td align="left" valign="top">Halliwell et al,<break/>2011 (United Kingdom) [<xref ref-type="bibr" rid="ref25">25</xref>]</td><td align="left" valign="top">10&#x2010; to 13-year-old females</td><td align="left" valign="top">T: n=37, C: n=29</td><td align="left" valign="top">Computer-based videos</td><td align="left" valign="top">Newspaper or magazine</td><td align="left" valign="top">None</td><td align="left" valign="top">EDI-BD<sup><xref ref-type="table-fn" rid="table1fn16">p</xref></sup>, BISS<sup><xref ref-type="table-fn" rid="table1fn17">q</xref></sup>, BES<sup><xref ref-type="table-fn" rid="table1fn18">r</xref></sup>, DEBQ<sup><xref ref-type="table-fn" rid="table1fn12">l</xref></sup>, EDI-DT</td></tr><tr><td align="left" valign="top">Franko et al, 2012<break/>(United States) [<xref ref-type="bibr" rid="ref47">47</xref>]</td><td align="left" valign="top">College women</td><td align="left" valign="top">T: n=32, C: n=32</td><td align="left" valign="top">Web page</td><td align="left" valign="top">Websites without information about eating</td><td align="left" valign="top">3 months</td><td align="left" valign="top">BSQ, SATAQ-3<sup><xref ref-type="table-fn" rid="table1fn19">s</xref></sup></td></tr><tr><td align="left" valign="top">Stice et al, 2012<break/>(United States) [<xref ref-type="bibr" rid="ref48">48</xref>]</td><td align="left" valign="top">Female college students</td><td align="left" valign="top">T: n=19, C: n=20</td><td align="left" valign="top">Web page</td><td align="left" valign="top">Educational brochure group: brochure</td><td align="left" valign="top">None</td><td align="left" valign="top">BPS-SD<sup><xref ref-type="table-fn" rid="table1fn20">t</xref></sup>, IBSS<sup><xref ref-type="table-fn" rid="table1fn21">u</xref></sup>-R, DRES<sup><xref ref-type="table-fn" rid="table1fn22">v</xref></sup>, BDI, EDDI<sup><xref ref-type="table-fn" rid="table1fn23">w</xref></sup></td></tr><tr><td align="left" valign="top">Serdar et al,<break/>2014 (United States) [<xref ref-type="bibr" rid="ref49">49</xref>]</td><td align="left" valign="top">18&#x2010;25 years old females</td><td align="left" valign="top">T: n=112, C: n=114</td><td align="left" valign="top">Web page</td><td align="left" valign="top">No intervention</td><td align="left" valign="top">8&#x2010;9 weeks</td><td align="left" valign="top">BES, EDDS<sup><xref ref-type="table-fn" rid="table1fn24">x</xref></sup>, IBSS-R<sup><xref ref-type="table-fn" rid="table1fn25">y</xref></sup></td></tr><tr><td align="left" valign="top">Zhong et al, 2016<break/>(China) [<xref ref-type="bibr" rid="ref50">50</xref>]</td><td align="left" valign="top">Female college students</td><td align="left" valign="top">T: n=33, C: n=31</td><td align="left" valign="top">Web page</td><td align="left" valign="top">No intervention</td><td align="left" valign="top">None</td><td align="left" valign="top">BPS-SD, IBSS-R</td></tr><tr><td align="left" valign="top">Toole et al,<break/>2016 (United States) [<xref ref-type="bibr" rid="ref51">51</xref>]</td><td align="left" valign="top">18&#x2010; to 21-year-old females</td><td align="left" valign="top">T: n=40, C: n=40</td><td align="left" valign="top">Social media</td><td align="left" valign="top">Waitlist control group</td><td align="left" valign="top">None</td><td align="left" valign="top">BSQ, SCS<sup><xref ref-type="table-fn" rid="table1fn26">z</xref></sup>, BAS<sup><xref ref-type="table-fn" rid="table1fn27">aa</xref></sup>, RSES<sup><xref ref-type="table-fn" rid="table1fn28">ab</xref></sup>, CSWS-AS<sup><xref ref-type="table-fn" rid="table1fn29">ac</xref></sup></td></tr><tr><td align="left" valign="top">Slater et al,2017<break/>(United Kingdom) [<xref ref-type="bibr" rid="ref52">52</xref>]</td><td align="left" valign="top">8&#x2010; to 9-year-old females</td><td align="left" valign="top">T: n=40, C: n=40</td><td align="left" valign="top">Internet games</td><td align="left" valign="top">Internet games without human figures</td><td align="left" valign="top">None</td><td align="left" valign="top">CFRS<sup><xref ref-type="table-fn" rid="table1fn30">ad</xref></sup>, MTST<sup><xref ref-type="table-fn" rid="table1fn31">ae</xref></sup></td></tr><tr><td align="left" valign="top">Rodgers et al,<break/>2018<break/>(United States) [<xref ref-type="bibr" rid="ref39">39</xref>]</td><td align="left" valign="top">14&#x2010; to 18-year-old adolescents</td><td align="left" valign="top">T: n=129, C: n=123</td><td align="left" valign="top">Mobile app</td><td align="left" valign="top">No intervention</td><td align="left" valign="top">12 weeks</td><td align="left" valign="top">PNSC<sup><xref ref-type="table-fn" rid="table1fn32">af</xref></sup>, SCS<sup><xref ref-type="table-fn" rid="table1fn33">ag</xref></sup>, BESAA<sup><xref ref-type="table-fn" rid="table1fn34">ah</xref></sup>, PAC<sup><xref ref-type="table-fn" rid="table1fn35">ai</xref></sup></td></tr><tr><td align="left" valign="top">Matheson et al, 2020 (United States) [<xref ref-type="bibr" rid="ref40">40</xref>]</td><td align="left" valign="top">7&#x2010; to 14-year-old children</td><td align="left" valign="top">T: n=442, C: n=446</td><td align="left" valign="top">Animated films</td><td align="left" valign="top">Animation without body image</td><td align="left" valign="top">None</td><td align="left" valign="top">VAS<sup><xref ref-type="table-fn" rid="table1fn36">aj</xref></sup>, CFRS</td></tr><tr><td align="left" valign="top">Seekis et al,<break/>2020 (Australia) [<xref ref-type="bibr" rid="ref53">53</xref>]</td><td align="left" valign="top">17&#x2010; to 21-year-old females</td><td align="left" valign="top">T: n=42, C: n=34</td><td align="left" valign="top">Social media</td><td align="left" valign="top">Waitlist control group</td><td align="left" valign="top">1 month,<break/>3 months</td><td align="left" valign="top">EDI-BD, EDI-DT, SAAS<sup><xref ref-type="table-fn" rid="table1fn37">ak</xref></sup>, UPACS<sup><xref ref-type="table-fn" rid="table1fn38">al</xref></sup>, BAS-2<sup><xref ref-type="table-fn" rid="table1fn39">am</xref></sup>, SCS-SF</td></tr><tr><td align="left" valign="top">Atkinson et al,<break/>2021 (United Kingdom) [<xref ref-type="bibr" rid="ref54">54</xref>]</td><td align="left" valign="top">Female undergraduates</td><td align="left" valign="top">T: n=67, C: n=65</td><td align="left" valign="top">computer-based videos</td><td align="left" valign="top">Documentary</td><td align="left" valign="top">1 week</td><td align="left" valign="top">VAS, BAS-2, BIAAQ<sup><xref ref-type="table-fn" rid="table1fn40">an</xref></sup>, SATAS<sup><xref ref-type="table-fn" rid="table1fn41">ao</xref></sup>, EDEQ, WSC<sup><xref ref-type="table-fn" rid="table1fn42">ap</xref></sup></td></tr><tr><td align="left" valign="top">Cerea et al, 2021 (Italy) [<xref ref-type="bibr" rid="ref41">41</xref>]</td><td align="left" valign="top">20&#x2010; to 25-year-old females</td><td align="left" valign="top">T: n=25, C: n=25</td><td align="left" valign="top">Mobile app</td><td align="left" valign="top">Waitlist control group</td><td align="left" valign="top">16 days</td><td align="left" valign="top">QDC<sup><xref ref-type="table-fn" rid="table1fn43">aq</xref></sup>, DASS-21<sup><xref ref-type="table-fn" rid="table1fn44">ar</xref></sup>, EDI-3<sup><xref ref-type="table-fn" rid="table1fn45">as</xref></sup></td></tr><tr><td align="left" valign="top">Garbett et al, 2023<break/>(Indonesia) [<xref ref-type="bibr" rid="ref55">55</xref>]</td><td align="left" valign="top">15&#x2010; to 19-year-old females</td><td align="left" valign="top">T: n=924, C: n=923</td><td align="left" valign="top">Social media&#x2013;based (Facebook and Instagram) videos</td><td align="left" valign="top">Waitlist control group</td><td align="left" valign="top">1 month</td><td align="left" valign="top">BESAA, SATAQ<sup><xref ref-type="table-fn" rid="table1fn46">at</xref></sup>, PNASC</td></tr><tr><td align="left" valign="top">Matheson et al, 2023 (Brazil) [<xref ref-type="bibr" rid="ref42">42</xref>]</td><td align="left" valign="top">13&#x2010; to 18-year-old Brazilian residents</td><td align="left" valign="top">T: n=355, C: n=443</td><td align="left" valign="top">Chatbot</td><td align="left" valign="top">Standard care</td><td align="left" valign="top">1 week,<break/>1 month</td><td align="left" valign="top">BESAA, PNASC, BIS-ES<sup><xref ref-type="table-fn" rid="table1fn47">au</xref></sup></td></tr><tr><td align="left" valign="top">Fardouly et al,<break/>2023 (Australia) [<xref ref-type="bibr" rid="ref56">56</xref>]</td><td align="left" valign="top">18&#x2010; to 25-year-old females</td><td align="left" valign="top">T: n=38, C: n=47</td><td align="left" valign="top">Social media</td><td align="left" valign="top">Use Facebook as usual</td><td align="left" valign="top">4 weeks</td><td align="left" valign="top">EDI-BD, PNASC, BAS, PACS</td></tr></tbody></table><table-wrap-foot><fn id="table1fn1"><p><sup>a</sup>T: intervention group.</p></fn><fn id="table1fn2"><p><sup>b</sup>C: control group.</p></fn><fn id="table1fn3"><p><sup>c</sup>BSQ: Body Shape Questionnaire.</p></fn><fn id="table1fn4"><p><sup>d</sup>EDI-DT: Eating Disorder Inventory-Drive for Thinness.</p></fn><fn id="table1fn5"><p><sup>e</sup>EDEQ: Eating Disorder Examination Questionnaire.</p></fn><fn id="table1fn6"><p><sup>f</sup>WCSC: Weight Concerns and Shape Concerns scale.</p></fn><fn id="table1fn7"><p><sup>g</sup>EDI: Eating Disorders Inventory.</p></fn><fn id="table1fn8"><p><sup>h</sup>SFRS: The Stunkard Figure Rating Scale.</p></fn><fn id="table1fn9"><p><sup>i</sup>SATA: Sociocultural Attitudes Toward Appearance.</p></fn><fn id="table1fn10"><p><sup>j</sup>BSQ-SF: Body Shape Questionnaire-Short form.</p></fn><fn id="table1fn11"><p><sup>k</sup>BCS: Body Comparison Scale.</p></fn><fn id="table1fn12"><p><sup>l</sup>DEBQ: Dutch Eating Behavior Questionnaire.</p></fn><fn id="table1fn13"><p><sup>m</sup>BDI: Beck Depression Inventory.</p></fn><fn id="table1fn14"><p><sup>n</sup>BESAA: Body Esteem Scale for Adolescents and Adults.</p></fn><fn id="table1fn15"><p><sup>o</sup>SPPA: Self-Perception Profile for Adolescents</p></fn><fn id="table1fn16"><p><sup>p</sup>EDI-BD: Body Dissatisfaction Subscale of the Eating Disorder Inventory.</p></fn><fn id="table1fn17"><p><sup>q</sup>BISS: Body Image State Scale.</p></fn><fn id="table1fn18"><p><sup>r</sup>BES: Body Esteem Scale.</p></fn><fn id="table1fn19"><p><sup>s</sup>SATAQ-3: Sociocultural Attitudes Towards Appearance Questionnaire-3.</p></fn><fn id="table1fn20"><p><sup>t</sup>BPS-SD: Satisfaction and Dissatisfaction with Body Parts Scale.</p></fn><fn id="table1fn21"><p><sup>u</sup>IBSS: Ideal-Body Stereotype Scale-Revised.</p></fn><fn id="table1fn22"><p><sup>v</sup>DRES: Dutch Restrained Eating Scale</p></fn><fn id="table1fn23"><p><sup>w</sup>EDDI: Eating Disorder Diagnostic Interview.</p></fn><fn id="table1fn24"><p><sup>x</sup>EDDS: Eating Disorder Diagnostic Scale.</p></fn><fn id="table1fn25"><p><sup>y</sup>IBSS-R: Ideal-Body Stereotype Scale-Revised.</p></fn><fn id="table1fn26"><p><sup>z</sup>SCS: Self-Compassion Scale.</p></fn><fn id="table1fn27"><p><sup>aa</sup>BAS: Body Appreciation Scale.</p></fn><fn id="table1fn28"><p><sup>ab</sup>RSES: Rosenberg Self-Esteem Scale.</p></fn><fn id="table1fn29"><p><sup>ac</sup>CSWS-AS: Contingencies of Self-Worth Scale-Appearance Subscale.</p></fn><fn id="table1fn30"><p><sup>ad</sup>CFRS: Child Figure Rating Scale.</p></fn><fn id="table1fn31"><p><sup>ae</sup>MTST: Modified Twenty Statements Test.</p></fn><fn id="table1fn32"><p><sup>af</sup>PNASC: Positive and Negative Affect Schedule for Children.</p></fn><fn id="table1fn33"><p><sup>ag</sup>SCS-SF: Self-Compassion Scale-Short-Form.</p></fn><fn id="table1fn34"><p><sup>ah</sup>BESAA: Body Esteem Scale for Adolescents and Adults.</p></fn><fn id="table1fn35"><p><sup>ai</sup>PACS: Physical Appearance Comparison Scale.</p></fn><fn id="table1fn36"><p><sup>aj</sup>VAS: visual analog scale.</p></fn><fn id="table1fn37"><p><sup>ak</sup>SAAS: Social Appearance Anxiety Scale.</p></fn><fn id="table1fn38"><p><sup>al</sup>UPACS: Upward Physical Appearance Comparison Scale.</p></fn><fn id="table1fn39"><p><sup>am</sup>BAS-2: Body Appreciation Scale-2.</p></fn><fn id="table1fn40"><p><sup>an</sup>BIAAQ: Body Image-Acceptance and Action Questionnaire.</p></fn><fn id="table1fn41"><p><sup>ao</sup>SATAS: Sociocultural Attitudes Toward Appearance Scale.</p></fn><fn id="table1fn42"><p><sup>ap</sup>WSC: Weight and Shape Concern.</p></fn><fn id="table1fn43"><p><sup>aq</sup>QDC: Questionario sul Dismorfismo Corporeo.</p></fn><fn id="table1fn44"><p><sup>ar</sup>DASS-21: Depression Anxiety Stress Scale-21.</p></fn><fn id="table1fn45"><p><sup>as</sup>EDI-3: Eating Disorder Inventory-3.</p></fn><fn id="table1fn46"><p><sup>at</sup>SATAQ: Sociocultural AttitudeTowardds Appearance Questionnaire.</p></fn><fn id="table1fn47"><p><sup>au</sup>BIS-ES: Body Image Self-Efficacy Scale.</p></fn></table-wrap-foot></table-wrap></sec><sec id="s3-3"><title>Risk of Bias in Studies</title><p>Of the 20 included studies, only 4 (20%) were assessed as low risk of bias, while 13 (65%) demonstrated high risk of bias, and 3 (15%) were categorized as moderate risk of bias (see <xref ref-type="supplementary-material" rid="app2">Multimedia Appendix 2</xref>).</p><sec id="s3-3-1"><title>Random Sequence Generation</title><p>This domain assesses whether the method used to generate the random sequence was adequate to prevent selection bias. Although all studies were reported to be RCTs, only 11 studies were assessed as having a low risk of bias in random sequence generation. Computer-generated random numbers were reported in 1 study [<xref ref-type="bibr" rid="ref46">46</xref>], and a random number table was reported in 3 studies [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref42">42</xref>]. Cluster or block randomization was reported in 4 studies [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]. Minimization functions in Qualtrics were reported in 2 studies [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref56">56</xref>]. It was reported in 1 study [<xref ref-type="bibr" rid="ref54">54</xref>] that whole timeslots were randomly allocated to a condition to avoid cross-contamination in an open computer laboratory, which was assessed as low risk of bias. However, 1 study [<xref ref-type="bibr" rid="ref44">44</xref>] was assessed as having a high risk of bias in random sequence generation because students were assigned to a group based on class schedule rather than randomization. The remaining 8 studies [<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref47">47</xref>-<xref ref-type="bibr" rid="ref52">52</xref>], which did not mention a specific method used to generate the random sequence, were assessed as unclear bias.</p></sec><sec id="s3-3-2"><title>Allocation Concealment</title><p>This domain evaluates whether the process of assigning participants to groups was concealed. Participants were reported to be randomly allocated to the intervention or control groups in all studies. Only 4 studies [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref53">53</xref>] reported the use of email to complete allocation concealment, which was assessed as a low risk of bias. In one study [<xref ref-type="bibr" rid="ref55">55</xref>] reported participants and researchers were not concealed from the randomized arm, which was assessed as a high risk of bias. Due to a lack of further details about allocation concealment, 15 studies [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>-<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] were considered as an unclear risk of bias.</p></sec><sec id="s3-3-3"><title>Blinding of Participants and Personnel</title><p>This domain assesses whether participants and researchers were blinded to group allocation. It was hard to achieve the blinding of participants or personnel because digital interventions were conducted in intervention groups and nondigital interventions were conducted in control groups in most studies involved. Internet-based or social media assessments and interventions were used in 6 studies [<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>-<xref ref-type="bibr" rid="ref55">55</xref>], which may be interpreted as blinding of participants and personnel. Among the 6 studies, 1 study [<xref ref-type="bibr" rid="ref45">45</xref>] reported that participants used a pseudonym. One study [<xref ref-type="bibr" rid="ref54">54</xref>] reported that all assessments were self-reported anonymously via computer. One study [<xref ref-type="bibr" rid="ref39">39</xref>] reported that assessments were housed on a survey software, and the procedure was identical for participants in both the intervention and control groups. Two studies [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref44">44</xref>] mentioned that participants were instructed not to discuss the study with other students to reduce potential cross-contamination, which might be seen as blinding participants and personnel. Four studies [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref49">49</xref>] were assessed as high risk of bias for their failure to blind participants. Seven studies [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] were assessed as unclear risk of bias due to a lack of further details being reported.</p></sec><sec id="s3-3-4"><title>Blinding of Outcome Assessment</title><p>This domain evaluates whether the outcome assessors were blinded to the intervention group assignments. Twelve studies were assessed as having a low risk of bias in the blinding of outcome assessment. One [<xref ref-type="bibr" rid="ref42">42</xref>] of these studies used dummy codes instead of participants&#x2019; names for outcome assessment. The outcome assessors in another 2 studies [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref55">55</xref>] were unaware of group allocation. Although assessors were not blinded, questionnaires were completed via website, social media, or application by participants in 6 studies [<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]. Another 3 studies [<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] were assessed as having a low risk of bias because questionnaires were sent by e-mail. Eight studies [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref46">46</xref>-<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>] were assessed as unclear due to the lack of clear information on whether the outcome assessors were blinded to the intervention group assignments. No study was evaluated as having a high risk of bias.</p></sec><sec id="s3-3-5"><title>Incomplete Outcome Data</title><p>This domain assesses whether there was any missing data and how it was handled. Fourteen studies were assessed to have a low risk of bias. Three [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref53">53</xref>] of these studies reported that no missing data emerged. One study [<xref ref-type="bibr" rid="ref45">45</xref>] reported the usage of baseline measures in place of missing posttreatment or follow-up data. One study [<xref ref-type="bibr" rid="ref46">46</xref>] claimed that its missing item values were replaced with the mean value of that participant&#x2019;s scale scores. Another 9 studies [<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref55">55</xref>] reported low attrition rates with balanced numbers across groups. Four studies [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] were assessed as high risk of bias because of high attrition rates after being randomized. Two studies [<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref52">52</xref>] did not report any information about the attrition rate, which was assessed to be at unclear risk of bias.</p></sec><sec id="s3-3-6"><title>Selective Reporting</title><p>This domain evaluates whether the study reported all the outcomes that were planned at the outset. One study [<xref ref-type="bibr" rid="ref49">49</xref>] was assessed to be at high risk of bias, as it mentioned that nonsignificant results were not reported. A total of 19 studies [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>-<xref ref-type="bibr" rid="ref56">56</xref>] were assessed as having a low risk of bias.</p></sec><sec id="s3-3-7"><title>Other Potential Sources of Bias</title><p>This domain assesses other potential biases not covered by the previous domains. Seven studies [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref55">55</xref>] with microinterventions lasting less than a week were assessed as unclear risk of bias. The rest appeared to be free of other biases (<xref ref-type="fig" rid="figure2">Figure 2</xref>) [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref47">47</xref>-<xref ref-type="bibr" rid="ref56">56</xref>]. A funnel plot of SE against SMD was generated for 2 outcomes with at least 10 studies: thin-ideal internalization and body dissatisfaction. A visual inspection of the plot for the 2 funnel plots revealed the presence of publication bias (<xref ref-type="supplementary-material" rid="app3">Multimedia Appendix 3</xref>).</p><fig position="float" id="figure2"><label>Figure 2.</label><caption><p>Risk of bias graph [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref38">38</xref>-<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref47">47</xref>-<xref ref-type="bibr" rid="ref56">56</xref>].</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="i-jmr_v14i1e72231_fig02.png"/></fig></sec><sec id="s3-3-8"><title>Results of Syntheses</title><sec id="s3-3-8-1"><title>The Effect of Digital Interventions on Body Image Satisfaction or Dissatisfaction</title><p>Three studies [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref54">54</xref>] reported the original data of body satisfaction among 1157 children and emerging adults by using the body satisfaction subscale of Visual Analogue Scale (VAS), and the higher scores indicated higher body satisfaction. The effect of digital interventions on body satisfaction was shown to be nonsignificant in the random-effect model (SMD=0.86, 95% CI &#x2212;0.17 to 1.89) with a high level of heterogeneity across studies (<italic>I<sup>2</sup></italic>=98%; <italic>P</italic>=.10). This may be due to a diverse rating system, that is, one study used the mean score for each item, while another two studies used a summed score. While the heterogeneity reduced (<italic>I</italic><sup>2</sup>=53%) after one study [<xref ref-type="bibr" rid="ref40">40</xref>] was excluded, and the result was a statistically significant conclusion with a small effect size (SMD=0.29, 95% CI 0.04 to 0.55; <italic>P</italic>=.02; <xref ref-type="fig" rid="figure3">Figure 3</xref> [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]).</p><fig position="float" id="figure3"><label>Figure 3.</label><caption><p>The effect of digital interventions on body satisfaction [<xref ref-type="bibr" rid="ref40">40</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref54">54</xref>].</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="i-jmr_v14i1e72231_fig03.png"/></fig><p>Four studies [<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] assessed the effect of digital interventions on body appreciation among 391 children and emerging adults. The pooled analysis showed a nonsignificant improvement in body appreciation between groups in the random-effects model with a high level of heterogeneity (SMD=0.62, 95% CI &#x2212;0.19 to 1.43; <italic>I<sup>2</sup></italic>=93%; <italic>P</italic>=.13). When excluding the study [<xref ref-type="bibr" rid="ref54">54</xref>] with the outlying effect size, the overall effect did not change (SMD=0.34, 95% CI &#x2212;0.41 to 1.09; <italic>P</italic>=.038; <xref ref-type="fig" rid="figure4">Figure 4</xref> [<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>]), and the heterogeneity remained high (<italic>I</italic><sup>2</sup>=88%).</p><fig position="float" id="figure4"><label>Figure 4.</label><caption><p>The effect of digital interventions on body appreciation [<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref54">54</xref>,<xref ref-type="bibr" rid="ref56">56</xref>].</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="i-jmr_v14i1e72231_fig04.png"/></fig><p>Ten RCTs [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>-<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] assessed the effect of digital interventions on body dissatisfaction among 594 participants, and the higher scores of the scales used in these studies indicated higher body dissatisfaction. The effect of digital interventions on body dissatisfaction was shown to be statistically significant with a small effect size in the random-effect model (SMD=&#x2212;0.38, 95% CI: &#x2212;0.63 to &#x2212;0.13; <italic>I</italic><sup>2</sup>=55%; <italic>P</italic>=.003; <xref ref-type="fig" rid="figure5">Figure 5</xref> [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>-<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref56">56</xref>]).</p><fig position="float" id="figure5"><label>Figure 5.</label><caption><p>The effect of digital interventions on body dissatisfaction [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>,<xref ref-type="bibr" rid="ref45">45</xref>-<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref56">56</xref>].</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="i-jmr_v14i1e72231_fig05.png"/></fig><p>Four RCTs [<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref54">54</xref>], including 357 participants, reported the effectiveness of digital interventions on the shape and weight concerns. Shape and weight concern is a facet of negative body image, and higher scores on the scales in the included studies reflected greater body dissatisfaction and less body image satisfaction. The pooled analysis showed non-significant improvement (SMD=&#x2212;0.59, 95% CI &#x2212;1.5 to 0.32) in shape and weight concern with high heterogeneity (<italic>I</italic><sup>2</sup>=93%; <italic>P</italic>=.21). There was no heterogeneity (<italic>I</italic><sup>2</sup>=0%) after one study [<xref ref-type="bibr" rid="ref54">54</xref>] was excluded (SMD=&#x2212;0.13, 95% CI &#x2212;0.41 to 0.14; <italic>P</italic>=.34; <xref ref-type="fig" rid="figure6">Figure 6</xref> [<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref54">54</xref>]). However, the result was not significantly different between groups.</p><fig position="float" id="figure6"><label>Figure 6.</label><caption><p>The effect of digital interventions on shape and weight concerns [<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref54">54</xref>].</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="i-jmr_v14i1e72231_fig06.png"/></fig><p>Three RCTs [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] measured the effects of digital interventions on physical appearance comparison among 419 participants. The higher the scores of the scales included in the studies, the more severe the physical appearance comparison among the participants. The result showed a statistically significant conclusion with high heterogeneity (SMD=&#x2212;0.52, 95% CI &#x2212;1.02 to &#x2212;0.01; <italic>I</italic><sup>2</sup>=82%<italic>; P</italic>=.004). The heterogeneity decreased to low with a small effect size (SMD=&#x2212;0.24, 95% CI &#x2212;0.45 to &#x2212;0.03; <italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.03; <xref ref-type="fig" rid="figure7">Figure 7</xref> [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref56">56</xref>]) when one study [<xref ref-type="bibr" rid="ref53">53</xref>] was excluded.</p><fig position="float" id="figure7"><label>Figure 7.</label><caption><p>The effect of digital interventions on physical appearance comparison [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref56">56</xref>].</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="i-jmr_v14i1e72231_fig07.png"/></fig></sec><sec id="s3-3-8-2"><title>Effect of Digital Interventions on Internalized Outcomes</title><p>Eleven RCTs [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref55">55</xref>] measured the effect of digital interventions on thin-ideal internalization among 3362 participants. The higher the scores of thin-ideal internalization, the stronger the desire to be thinner, not objectively thin. The pooled analysis showed a significant improvement in thin-ideal internalization in the random-effect model (SMD=&#x2212;0.64, 95% CI &#x2212;1.09 to &#x2212;0.18) with high heterogeneity (<italic>I</italic><sup>2</sup>=94; <italic>P</italic>&#x003C;.001). The heterogeneity reduced to moderate (<italic>I</italic><sup>2</sup>=41%) when one study [<xref ref-type="bibr" rid="ref49">49</xref>] was excluded, while the result remained a small and significant effect size (SMD=&#x2212;0.28, 95% CI &#x2212;0.36 to &#x2212;0.20; <italic>P</italic>=.001; <xref ref-type="fig" rid="figure8">Figure 8</xref> [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref55">55</xref>]).</p><fig position="float" id="figure8"><label>Figure 8.</label><caption><p>The effect of digital interventions on thin-ideal internalization [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref43">43</xref>-<xref ref-type="bibr" rid="ref50">50</xref>,<xref ref-type="bibr" rid="ref53">53</xref>,<xref ref-type="bibr" rid="ref55">55</xref>].</p></caption><graphic alt-version="no" mimetype="image" position="float" xlink:type="simple" xlink:href="i-jmr_v14i1e72231_fig08.png"/></fig><p>Six RCTs [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref55">55</xref>] measured the effectiveness of digital interventions on self-esteem among 3632 participants. Higher scores for self-esteem indicate higher body image satisfaction. The result depicted self-esteem in the experimental group was significantly better than the control group with high heterogeneity (SMD=0.28, 95% CI 0.08-0.47; <italic>I</italic><sup>2</sup>=81%; <italic>P</italic>=.005). When excluding the study [<xref ref-type="bibr" rid="ref49">49</xref>], the intervention effect on self-esteem remained significant with a small effect size (SMD=0.14, 95% CI 0.07-0.21) with low heterogeneity (<italic>I</italic><sup>2</sup>=21%, <italic>P</italic>&#x003C;.001; <xref ref-type="supplementary-material" rid="app4">Multimedia Appendix 4</xref>).</p><p>Meta-analysis results on 3 studies [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>] with 385 participants showed that self-compassion in the experimental group was significantly better than the control group with a high level of heterogeneity (SMD=0.73, 95% CI 0.25-1.2; <italic>I</italic><sup>2</sup>=76%; <italic>P</italic>=.003). The heterogeneity reduced to moderate (<italic>I</italic><sup>2</sup>=35%) after excluding the study [<xref ref-type="bibr" rid="ref53">53</xref>], and the intervention effect on self-compassion remained significant with a medium effect size (SMD=0.55, 95% CI 0.33-0.78; <italic>P</italic>=.001; <xref ref-type="supplementary-material" rid="app5">Multimedia Appendix 5</xref>).</p><p>Two RCTs [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] assessed the effect of digital interventions on self-objectification among 191 participants. Self-objectification refers to conceptualizing one&#x2019;s own body as objects to be scrutinized by others, and higher levels of self-objectification indicate greater body dissatisfaction. The pooled analysis showed that self-objectification in the experimental groups was not significantly different from the control groups (SMD=&#x2212;0.05, 95% CI &#x2212;0.33 to 0.24; <italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.75; <xref ref-type="supplementary-material" rid="app6">Multimedia Appendix 6</xref>).</p></sec><sec id="s3-3-8-3"><title>Effect of Digital Interventions on Negative Affect</title><p>Four RCTs [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref56">56</xref>] assessed the effect of digital interventions on negative affect among 2981 participants. The negative effects include afraid, upset, shame, hostility, and misery, and higher scores of negative affect indicate higher body dissatisfaction. The pooled analysis showed that the negative affect in the experimental groups was not superior to the control groups (SMD=&#x2212;0.07, 95% CI &#x2212;0.14 to 0.00; <italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.05; <xref ref-type="supplementary-material" rid="app7">Multimedia Appendix 7</xref>).</p><p>Four RCTs reported the effect of digital interventions on depression, anxiety, and stress among 342 participants by using the Beck Depression Inventory (BDI) [<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref48">48</xref>], the Depression Anxiety Stress Scale-21 (DASS-21) [<xref ref-type="bibr" rid="ref41">41</xref>], and the Social Appearance Anxiety Scale (SAAS) [<xref ref-type="bibr" rid="ref53">53</xref>]. The higher scores in the 3 scales indicate higher depression, anxiety, and stress. Owing to the assessment of different psychological outcomes, the data could not be synthesized in the 2 studies [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref53">53</xref>], and there was no statistically significant improvement found in the 2 studies, separately. However, the pooled analysis of the BDI group showed a significant improvement in depression in the fixed-effects model with a medium effect size (SMD=&#x2212;0.59, 95% CI &#x2212;0.97 to &#x2212;0.21; <italic>I</italic><sup>2</sup>=0%; <italic>P</italic>=.002; <xref ref-type="supplementary-material" rid="app8">Multimedia Appendix 8</xref>).</p></sec><sec id="s3-3-8-4"><title>Effect of Digital Interventions on Eating Behaviors</title><p>Four RCTs [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref49">49</xref>] assessed the effect of digital interventions on eating disorders among 457 participants. The pooled analysis of eating disorders showed there was no statistically significant difference between groups (SMD=&#x2212;0.37, 95% CI &#x2212;1.36 to 0.6) with high heterogeneity (<italic>I</italic><sup>2</sup>=95%; <italic>P</italic>=.45). The heterogeneity decreased to low (<italic>I</italic><sup>2</sup>=0%) after one study [<xref ref-type="bibr" rid="ref49">49</xref>] was excluded, and the result remained no significant difference between groups (SMD=&#x2212;0.04, 95% CI &#x2212;0.31 to 0.22; <italic>P</italic>=.75; <xref ref-type="supplementary-material" rid="app9">Multimedia Appendix 9</xref>).</p><p>Two RCTs [<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref48">48</xref>] assessed the effect of digital interventions on eating restraint among 203 participants. Higher scores of eating restraint are indicative of greater use of extreme weight loss behaviors. The pooled analysis of eating restraint showed that there was no statistically significant difference between groups (SMD=&#x2212;0.36, 95% CI &#x2212;0.71 to 0.00; <italic>I</italic><sup>2</sup>=31%; <italic>P</italic>=.05; <xref ref-type="supplementary-material" rid="app10">Multimedia Appendix 10</xref>).</p></sec></sec></sec></sec><sec id="s4" sec-type="discussion"><title>Discussion</title><sec id="s4-1"><title>Principal Findings</title><p>This systematic review and meta-analysis synthesized evidence from 20 RCTs involving 5251 participants to evaluate the effectiveness of digital interventions (eg, web pages, mobile apps, and social media) on body dissatisfaction and related outcomes. Key findings indicated that digital interventions significantly improved body dissatisfaction, physical appearance comparison, thin-ideal internalization, self-esteem, self-compassion, and depression, with small to medium effect sizes. However, there was substantial heterogeneity across studies, and potential publication bias was detected. Digital interventions did not significantly improve negative affect (including depression and anxiety) and eating behaviors.</p></sec><sec id="s4-2"><title>Study Characteristics</title><p>All the included studies have been conducted in the last 2 decades, but only 2 studies have been done in developing countries. This indicates that high-quality RCTs need to be conducted further in this area, especially to explore their effectiveness on body dissatisfaction in different ethnic and cultural backgrounds in developing countries [<xref ref-type="bibr" rid="ref57">57</xref>]. Ten out of twenty included studies selected different theories or models to motivate participants to reduce the pursuit of thin-ideal internalization, to improve emotional regulation, such as self-compassion, and to develop coping strategies with the involvement of parents, peers, and the media. The cognitive dissonance theory, cognitive behavioral theory, and sociocultural theory were recognized as the most widely mentioned theories to reduce body dissatisfaction in the studies. The average sample size was high 200s, but most studies included participants of less than 100. This would result from the narrow age range and the diagnosis of anorexia nervosa and other eating or psychiatric disorders among children and emerging adults in the inclusion criteria. The participants&#x2019; ages ranged from 7 to 25 years old, and 6 studies included those younger than 14 years old in private or public schools as participants. Nearly 80% of participants were females in this review, and 9 studies only included female college students or undergraduates as participants, which accounted for 16.7% of the total participants. This can indicate that females would be more likely to experience body dissatisfaction, like other studies [<xref ref-type="bibr" rid="ref58">58</xref>].</p></sec><sec id="s4-3"><title>Comparison to Previous Work</title><p>The meta-analysis revealed that digital interventions showed a small to medium effect across most outcomes in body satisfaction and internalized outcomes, and the result was similar to another systematic review [<xref ref-type="bibr" rid="ref24">24</xref>]. In the systematic review, although there was no quantitative synthesis, body dissatisfaction, body esteem, body appreciation, and other body image outcomes were also included in the review to explore the effectiveness of digital interventions in emerging adults and emerging adults. The results showed 8 out of 15 studies reported digital interventions were effective in improving at least one body image outcome from pre-post interventions with mostly small to medium effect sizes. This means digital interventions are superior to some traditional interventions, such as brochures, documentaries, newspapers, or magazines. It may result from the advantages of digital interventions, such as real-time feedback and motivation enhancement [<xref ref-type="bibr" rid="ref59">59</xref>], and anonymity of platforms [<xref ref-type="bibr" rid="ref60">60</xref>], which could reduce the shame and social anxiety emerging adults face when dealing with body image-related issues. However, given that effect sizes were small to medium, it would be caused by the following reasons. First, the intervention duration of this meta-analysis was 6 weeks on average. Second, digital intervention had its limitations, such as being incapable of genuinely caring about one&#x2019;s feelings during the intervention process. This indicated that digital interventions with an in-person element would be associated with greater effectiveness in body image [<xref ref-type="bibr" rid="ref61">61</xref>].</p><p>Digital interventions did not significantly reduce the negative affect (including depression and anxiety) and eating behaviors. However, another 2 systematic reviews [<xref ref-type="bibr" rid="ref61">61</xref>,<xref ref-type="bibr" rid="ref62">62</xref>] found a significant effect of digital interventions on depression and anxiety among emerging adults and emerging adults. This would result from the contents of the digital interventions. The digital interventions of the 2 systematic reviews specifically targeted mental health disorders, including depression and anxiety. However, this meta-analysis mainly targeted improving body dissatisfaction with depression and anxiety as secondary outcomes in some studies included. Furthermore, it indicated that digital psychotherapy did not significantly reduce both eating disorders and restrained eating in this meta-analysis. This would be caused by the following reasons. First, no more than 4 RCTs were included in this meta-analysis to explore the effects of digital interventions on eating disorders or restraint eating. Second, the age of participants in this meta-analysis ranged from 7 to 25 years. Especially for the emerging adults who were predominant participants, who have already established eating behavior habits, which would be so ingrained and resistant to change through short-term digital psychological therapy. According to the Transtheoretical Model [<xref ref-type="bibr" rid="ref63">63</xref>], the process of behavior change is complicated with 6 different stages, and it would not be easy to change eating behaviors. In addition, the digital interventions in the 20 included RCTs were aimed at addressing body dissatisfaction rather than specific eating disorder symptoms, which might account for the insignificant outcome in changing eating behaviors.</p></sec><sec id="s4-4"><title>Implications for Clinical Practice</title><p>The findings suggest that digital interventions can serve as scalable and cost-effective supplementary tools to improve body dissatisfaction in children and emerging adults. Clinicians may recommend digital interventions as adjuncts to traditional face-to-face therapies, particularly for individuals with limited access to in-person mental health services due to cost, stigma, or geographic barriers. Body dissatisfaction, thin-ideal internalization, eating disorders, and negative affect should be addressed simultaneously in a single intervention to verify the effectiveness of digital interventions in the future. Future studies should be conducted in Asia and some other low-income countries, as this review found that studies in these regions are lacking. Furthermore, the quality of included studies held room for improvement.</p></sec><sec id="s4-5"><title>Limitations</title><p>This systematic review has several limitations. First, the high heterogeneity in meta-analysis may result from the use of different scales to assess the same outcomes, even using different versions or varying score systems (eg, summed versus mean scores) of the same scales. However, the SMD was selected to express the size of the intervention effect, instead of the mean difference. Second, confidence in the meta-analysis was limited because waitlist groups were set in 7 studies, and assessment-only control (receive no intervention) groups were set in another 4 studies, rather than active control groups. Third, there was insufficient data on long&#x2010;term follow&#x2010;up and a potential gap that future RCTs can look to fill. Specific tactics could be analyzed to maintain engagement in body image interventions for children and emerging adults, such as integrating digital interventions into existing curricula. Fourth, the quality of included studies held room for improvement, with most of the RCTs included being rated as &#x201C;unclear risk&#x201D; for bias. Fifth, publication bias may have influenced the results, particularly for outcomes with small sample sizes, highlighting the need for larger, registered RCTs.</p></sec><sec id="s4-6"><title>Conclusion</title><p>Digital interventions could help children and emerging adults improve body satisfaction or dissatisfaction, physical appearance comparison, thin-ideal internalization, self-esteem, self-compassion, and depression. Because of the limitations, the results should be generalized with caution. In the future, high-quality RCTs with longer intervention duration and long-term follow-up should be conducted, especially in different races and cultures in transitional countries.</p></sec></sec></body><back><ack><p>The authors would like to thank Professor Roger Watson for his help with the review statement and English language editing.</p></ack><notes><sec><title>Data Availability</title><p>The datasets generated and analyzed during this study are available from the corresponding author on reasonable request.</p></sec></notes><fn-group><fn fn-type="con"><p>LL: Writing &#x2013; original draft, Conceptualization, Data curation, Methodology, Software. JY: Writing &#x2013; original draft, Conceptualization, Data curation. FT: Conceptualization, Data curation, Methodology. XY: Conceptualization, Data curation, Methodology. HL: Conceptualization, Methodology. YC: Supervision, Writing &#x2013; review &#x0026; editing. XLZ: Supervision, Writing &#x2013; review &#x0026; editing.</p></fn><fn fn-type="conflict"><p>None declared.</p></fn></fn-group><glossary><title>Abbreviations</title><def-list><def-item><term id="abb1">BDI</term><def><p>Beck Depression Inventory</p></def></def-item><def-item><term id="abb2">BIS</term><def><p>behavior interventions and supports</p></def></def-item><def-item><term id="abb3">CBT</term><def><p>cognitive-behavioral therapy</p></def></def-item><def-item><term id="abb4">CNKI</term><def><p>China National Knowledge Infrastructure</p></def></def-item><def-item><term id="abb5">DASS-21</term><def><p>Depression Anxiety Stress Scale-21</p></def></def-item><def-item><term id="abb6">EBSCO</term><def><p>Elton B. 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[<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref38">38</xref>,<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref49">49</xref>,<xref ref-type="bibr" rid="ref55">55</xref>].</p><media xlink:href="i-jmr_v14i1e72231_app4.doc" xlink:title="DOC File, 33 KB"/></supplementary-material><supplementary-material id="app5"><label>Multimedia Appendix 5</label><p>The effect of digital interventions on self-compassion [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref51">51</xref>,<xref ref-type="bibr" rid="ref53">53</xref>].</p><media xlink:href="i-jmr_v14i1e72231_app5.doc" xlink:title="DOC File, 31 KB"/></supplementary-material><supplementary-material id="app6"><label>Multimedia Appendix 6</label><p>The effect of digital interventions on self-objectification [<xref ref-type="bibr" rid="ref52">52</xref>,<xref ref-type="bibr" rid="ref56">56</xref>].</p><media xlink:href="i-jmr_v14i1e72231_app6.doc" xlink:title="DOC File, 30 KB"/></supplementary-material><supplementary-material id="app7"><label>Multimedia Appendix 7</label><p>The effect of digital interventions on negative affect [<xref ref-type="bibr" rid="ref39">39</xref>,<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref55">55</xref>,<xref ref-type="bibr" rid="ref56">56</xref>].</p><media xlink:href="i-jmr_v14i1e72231_app7.doc" xlink:title="DOC File, 32 KB"/></supplementary-material><supplementary-material id="app8"><label>Multimedia Appendix 8</label><p>The effect of digital interventions on depression [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref53">53</xref>].</p><media xlink:href="i-jmr_v14i1e72231_app8.doc" xlink:title="DOC File, 30 KB"/></supplementary-material><supplementary-material id="app9"><label>Multimedia Appendix 9</label><p>The effect of digital interventions on eating disorders [<xref ref-type="bibr" rid="ref41">41</xref>,<xref ref-type="bibr" rid="ref44">44</xref>,<xref ref-type="bibr" rid="ref45">45</xref>,<xref ref-type="bibr" rid="ref49">49</xref>].</p><media xlink:href="i-jmr_v14i1e72231_app9.doc" xlink:title="DOC File, 32 KB"/></supplementary-material><supplementary-material id="app10"><label>Multimedia Appendix 10</label><p>The effect of digital interventions on eating restraint [<xref ref-type="bibr" rid="ref46">46</xref>,<xref ref-type="bibr" rid="ref48">48</xref>].</p><media xlink:href="i-jmr_v14i1e72231_app10.doc" xlink:title="DOC File, 30 KB"/></supplementary-material><supplementary-material id="app11"><label>Checklist 1</label><p>PRISMA 2020 checklist.</p><media xlink:href="i-jmr_v14i1e72231_app11.doc" xlink:title="DOC File, 335 KB"/></supplementary-material></app-group></back></article>