<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "http://dtd.nlm.nih.gov/publishing/2.0/journalpublishing.dtd">
<?covid-19-tdm?>
<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">IJMR</journal-id>
      <journal-id journal-id-type="nlm-ta">Interact J Med Res</journal-id>
      <journal-title>Interactive Journal of Medical Research</journal-title>
      <issn pub-type="epub">1929-073X</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v12i1e40883</article-id>
      <article-id pub-id-type="pmid">36718815</article-id>
      <article-id pub-id-type="doi">10.2196/40883</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>COVID-19 in Vietnam and Its Impact on Road Trauma: Retrospective Study Based on National Data</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Mavragani</surname>
            <given-names>Amaryllis</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Thang</surname>
            <given-names>Tran</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Phuong</surname>
            <given-names>Nguyen</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Nguyen</surname>
            <given-names>Ba Tuan</given-names>
          </name>
          <degrees>MD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <address>
            <institution>Menzies Institute for Medical Research</institution>
            <institution>University of Tasmania</institution>
            <addr-line>17 Liverpool Street</addr-line>
            <addr-line>Hobart, 7000</addr-line>
            <country>Australia</country>
            <phone>61 460918919</phone>
            <email>batuan.nguyen@utas.edu.au</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-1496-8376</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author">
          <name name-style="western">
            <surname>Blizzard</surname>
            <given-names>Christopher Leigh</given-names>
          </name>
          <degrees>DPhil, Prof Dr</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-9541-6943</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author">
          <name name-style="western">
            <surname>Palmer</surname>
            <given-names>Andrew</given-names>
          </name>
          <degrees>DPhil</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-9703-7891</ext-link>
        </contrib>
        <contrib id="contrib4" contrib-type="author">
          <name name-style="western">
            <surname>Nguyen</surname>
            <given-names>Huu Tu</given-names>
          </name>
          <degrees>MD, DPhil, Prof Dr</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-8310-5216</ext-link>
        </contrib>
        <contrib id="contrib5" contrib-type="author">
          <name name-style="western">
            <surname>Cong Quyet</surname>
            <given-names>Thang</given-names>
          </name>
          <degrees>MD, DPhil, Prof Dr</degrees>
          <xref rid="aff2" ref-type="aff">2</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9132-4235</ext-link>
        </contrib>
        <contrib id="contrib6" contrib-type="author">
          <name name-style="western">
            <surname>Tran</surname>
            <given-names>Viet</given-names>
          </name>
          <degrees>MBBS</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff3" ref-type="aff">3</xref>
          <xref rid="aff4" ref-type="aff">4</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-8890-1457</ext-link>
        </contrib>
        <contrib id="contrib7" contrib-type="author">
          <name name-style="western">
            <surname>Nelson</surname>
            <given-names>Mark</given-names>
          </name>
          <degrees>MBBS, DPhil</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0001-9941-7161</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Menzies Institute for Medical Research</institution>
        <institution>University of Tasmania</institution>
        <addr-line>Hobart</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Hanoi Medical University</institution>
        <addr-line>Hanoi</addr-line>
        <country>Vietnam</country>
      </aff>
      <aff id="aff3">
        <label>3</label>
        <institution>Tasmanian School of Medicine</institution>
        <institution>University of Tasmania</institution>
        <addr-line>Hobart</addr-line>
        <country>Australia</country>
      </aff>
      <aff id="aff4">
        <label>4</label>
        <institution>Tasmanian Health Service</institution>
        <addr-line>Hobart</addr-line>
        <country>Australia</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Ba Tuan Nguyen <email>batuan.nguyen@utas.edu.au</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <year>2023</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>6</day>
        <month>2</month>
        <year>2023</year>
      </pub-date>
      <volume>12</volume>
      <elocation-id>e40883</elocation-id>
      <history>
        <date date-type="received">
          <day>5</day>
          <month>9</month>
          <year>2022</year>
        </date>
        <date date-type="rev-request">
          <day>7</day>
          <month>10</month>
          <year>2022</year>
        </date>
        <date date-type="rev-recd">
          <day>19</day>
          <month>12</month>
          <year>2022</year>
        </date>
        <date date-type="accepted">
          <day>31</day>
          <month>1</month>
          <year>2023</year>
        </date>
      </history>
      <copyright-statement>©Ba Tuan Nguyen, Christopher Leigh Blizzard, Andrew Palmer, Huu Tu Nguyen, Thang Cong Quyet, Viet Tran, Mark Nelson. Originally published in the Interactive Journal of Medical Research (https://www.i-jmr.org/), 06.02.2023.</copyright-statement>
      <copyright-year>2023</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Interactive Journal of Medical Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.i-jmr.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://www.i-jmr.org/2023/1/e40883" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>Despite significant improvement in the last decade, road trauma remains a substantial contributor to deaths in Vietnam. The COVID-19 pandemic necessitated public health measures that had an unforeseen benefit on road trauma in high-income countries. We investigate if this reduction was also seen in a low- to middle-income country like Vietnam.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>Our aim was to investigate how the COVID-19 pandemic and the government policies implemented in response to it impacted road trauma fatalities in Vietnam. We also compared this impact to other government policies related to road trauma implemented in the preceding 14 years (2007-2020).</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>COVID-19 data were extracted from the Vietnamese Ministry of Health database. Road traffic deaths from 2007 to 2021 were derived from the Vietnamese General Statistical Office. We used Stata software (version 17; StataCorp) for statistical analysis. Poisson regression modeling was used to estimate trends in road fatality rates based on annual national mortality data for the 2007-2021 period. The actual change in road traffic mortality in 2021 was compared with calculated figures to demonstrate the effect of COVID-19 on road trauma fatalities. We also compared this impact to other government policies that aimed to reduce traffic-related fatalities from 2007 to 2020.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>Between 2007 and 2020, the number of annual road traffic deaths decreased by more than 50%, from 15.3 to 7 per 100,000 population, resulting in an average reduction of 5.4% per annum. We estimated that the road traffic mortality rate declined by 12.1% (95% CI 8.9-15.3%) in 2021 relative to this trend. The actual number of road trauma deaths fell by 16.4%. This reduction was largely seen from August to October 2021 when lockdown and social distancing measures were in force.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>In 2021, the road traffic–related death reduction in Vietnam was 3 times greater than the trend seen in the preceding 14 years. The public health response to the COVID-19 pandemic in Vietnam was associated with a third of this reduction. It can thus be concluded that government policies implemented to address the COVID-19 pandemic resulted in a 4.3% decrease in road traffic deaths in 2021. This has been observed in high-income countries, but we have demonstrated this for the first time in a low- and middle-income country.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>COVID-19</kwd>
        <kwd>impact</kwd>
        <kwd>road trauma</kwd>
        <kwd>low- and middle-income country</kwd>
        <kwd>LMIC</kwd>
        <kwd>mortality</kwd>
        <kwd>pandemic</kwd>
        <kwd>trauma</kwd>
        <kwd>social distancing</kwd>
        <kwd>lockdown</kwd>
        <kwd>Vietnam</kwd>
        <kwd>disease</kwd>
        <kwd>policy</kwd>
        <kwd>deaths</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <sec>
        <title>Background</title>
        <p>COVID-19 is an infectious disease caused by the SARS-CoV-2 virus, which was discovered in Wuhan, China, on December 31, 2019 [<xref ref-type="bibr" rid="ref1">1</xref>]. In Vietnam, the first confirmed COVID-19 case was recorded in late January 2020 [<xref ref-type="bibr" rid="ref2">2</xref>]. During that year, while most countries around the world struggled against the pandemic, Vietnam was considered one of the safest places in terms of COVID-19 community transmission [<xref ref-type="bibr" rid="ref3">3</xref>]. This was due to a strict “zero-COVID” government policy that included closure of the Vietnam-China border, restrictions to air travel from any affected countries, quarantining of infected patients and all close contacts, mandatory use of masks in public places, closure of all nonessential services, and use of rapid antigen or real-time–polymerase chain reaction testing for all suspected cases [<xref ref-type="bibr" rid="ref4">4</xref>]. However, this changed quickly in the following year. While most affected countries were reopening, a wave of COVID-19 spread across Vietnam. There were 4 waves of COVID-19 outbreak in Vietnam [<xref ref-type="bibr" rid="ref5">5</xref>], but the fourth outbreak, which started in April 2021 and was caused by the Delta variant, was the most catastrophic [<xref ref-type="bibr" rid="ref6">6</xref>]. To control this situation, as was done in other countries [<xref ref-type="bibr" rid="ref7">7</xref>], social distancing and lockdown strategies were applied in Vietnam by the central government to local government areas according to their disease burden [<xref ref-type="bibr" rid="ref8">8</xref>]. The Vietnamese government placed approximately a third of the national population (including the 2 largest cities, Hanoi and Ho Chi Minh City) under lockdown starting on July 23, 2021. This lasted for about 3 months and was gradually relaxed in November 2021 as the pandemic was brought under control.</p>
        <p>Another contemporary “pandemic” is road trauma, which has been a significant contributor to morbidity and mortality in Vietnam and other low- and middle-income countries (LMICs) for decades [<xref ref-type="bibr" rid="ref9">9</xref>]. The risk of road traffic death in LMICs over the last decade was more than 3 times higher than in high-income countries (HICs) such as the United States, United Kingdom, and Australia [<xref ref-type="bibr" rid="ref10">10</xref>]. In the last 15 years in Vietnam, approximately 9000 people per annum have been killed in road accidents, with an equal number hospitalized [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref12">12</xref>]. This problem has been driven by poor infrastructure and the dominance of the motorcycle as the mode of transport, often overladen with passengers and cargo [<xref ref-type="bibr" rid="ref9">9</xref>]. To address this problem, the Vietnamese government legislated multiple public health measures. In 2008, helmets became mandatory for all motorcycle riders and their passengers [<xref ref-type="bibr" rid="ref13">13</xref>]. Mandatory seatbelt use in other vehicles was introduced in the same year [<xref ref-type="bibr" rid="ref13">13</xref>]. Media campaigns and public traffic law education have also been ubiquitous since this time. Subsequently, road deaths have steadily declined [<xref ref-type="bibr" rid="ref14">14</xref>].</p>
        <p>The lockdown and social distancing measures were implemented to reduce transmission and death due to COVID-19 but may have had an unforeseen benefit on road trauma. For example, social distancing may limit the number of passengers in an individual vehicle and, hence, reduce the number of people exposed to trauma should that vehicle crash. Lockdowns also reduce exposure since population movements are limited to essential travel and cross-border movements are restricted. Reductions have been seen in most HICs [<xref ref-type="bibr" rid="ref15">15</xref>]. For example, in Australia where such interventions were widely enforced, there was a 7% reduction in road trauma deaths in 2020 compared with 2019 [<xref ref-type="bibr" rid="ref15">15</xref>-<xref ref-type="bibr" rid="ref17">17</xref>]. Our study aimed to investigate if those reductions were also seen in an LMIC like Vietnam.</p>
      </sec>
      <sec>
        <title>Objective</title>
        <p>We aimed to investigate the effect of the COVID-19 pandemic and the Vietnamese government’s policies in response to it on road trauma fatalities. We also compared this impact with other improvements related to government policies over the past 14 years (2007-2020) regarding road trauma management.</p>
      </sec>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Data Sources</title>
        <p>COVID-19 data were extracted from the Vietnamese Ministry of Health database [<xref ref-type="bibr" rid="ref18">18</xref>]. Road traffic mortality (2007-2021) was derived from the Vietnamese General Statistical Office [<xref ref-type="bibr" rid="ref19">19</xref>]. All data sources were anonymous or deidentified for privacy and confidentiality protection.</p>
      </sec>
      <sec>
        <title>Statistical Methodology</title>
        <p>We used Stata software (version 17; StataCorp) for statistical analysis. Poisson regression modeling, with the logarithm of the national population of Vietnam for each year included as an offset, was used to estimate trends in the rates of road fatalities from the annual national mortality data for the 2007-2021 period. The Poisson regression model related the expected number <italic>E</italic>(<italic>Y<sub>t</sub></italic>) of road fatalities <italic>Y<sub>t</sub></italic> in Vietnam in each year <italic>t</italic> (<italic>t</italic>=2007, 2008,…, 2021) to a vector of covariates <bold>x</bold><italic><sub>t</sub></italic> for that year according to the log-linear form:</p>
        <p>
          <disp-formula>
            <graphic xlink:href="ijmr_v12i1e40883_fig5.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
          </disp-formula>
        </p>
        <p>where <italic>pop<sub>t</sub></italic> is the estimated national population of Vietnam for year <italic>t</italic> and In(<italic>pop<sub>t</sub></italic>) is its logarithm entered as an offset (a covariate with a coefficient of unity), and <inline-graphic xlink:href="ijmr_v12i1e40883_fig6.png" xlink:type="simple" mimetype="image"/> is the vector of coefficients to be estimated. The final form of the linear predictor <bold>x</bold><italic><sub>t</sub></italic> <inline-graphic xlink:href="ijmr_v12i1e40883_fig7.png" xlink:type="simple" mimetype="image"/> is as follows:</p>
        <p>
          <disp-formula>
            <graphic xlink:href="ijmr_v12i1e40883_fig8.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
          </disp-formula>
        </p>
        <p>where t<sub>2008</sub>, t<sub>2012</sub>, t<sub>2020</sub>, and t<sub>2021</sub> are step functions that allow the vertical position of the quadratic line of best fit to shift up or down (a level change) in the years nominated (2008, 2012, 2020, and 2021) and subsequent years. For example, the step function t<sub>2008</sub> was defined as:</p>
        <p>
          <disp-formula>
            <graphic xlink:href="ijmr_v12i1e40883_fig9.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
          </disp-formula>
        </p>
        <p>The exponential value of the estimated coefficient <inline-graphic xlink:href="ijmr_v12i1e40883_fig10.png" xlink:type="simple" mimetype="image"/> is an estimate of the percentage change (step up or step down) that occurred in the year 2008. The other step functions were defined in analogous ways. The 4 years involved were chosen a priori as the years that helmet and seatbelt use were made mandatory (2008), traffic safety regulations were strengthened (2012), impaired driving laws were fortified (2020), and the COVID-19 response was implemented (2021). Having annual data only, there was neither capacity nor need to estimate the lag in months between implementation and impact, nor was it necessary to use segmented regression methods. The final form of the linear predictor was selected after fitting interaction terms between each of the step functions and the covariates (<italic>t</italic> and <italic>t</italic><sup>2</sup>) for year to allow the slope of the trend line to change. In every case, the null hypothesis that no change in slope had occurred was accepted (<italic>P</italic>&#62;.05). There was no evidence of extra-Poisson variation (deviance goodness-of-fit test: <italic>P</italic>=.13) or of autocorrelation in the residuals (Q-statistic: <italic>P</italic>&#62;.05 at each lag). The actual change in road traffic mortality in 2021 was compared with calculated figures to demonstrate the effect of COVID-19 measures on road trauma fatality.</p>
      </sec>
      <sec>
        <title>Ethical Considerations</title>
        <p>The study was approved for human ethics exemption (H0027318 [H-84839]), issued on April 6, 2022, by the Human Research Ethics Committee of the University of Tasmania.</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>The COVID-19 Pandemic in Vietnam</title>
        <p>There were fewer than 3000 confirmed COVID-19 cases and 35 COVID-19–related deaths during the initial 15 months since the first recorded case in January 2020. However, with the appearance of the Delta variant, the number of confirmed cases escalated exponentially from 373 in April 2021 to 10,730 in June 2021, reaching a peak of over 360,000 in September and a second peak in November (<xref rid="figure1" ref-type="fig">Figure 1</xref>). Similarly, the number of deaths due to COVID-19 rapidly escalated from 18 in May 2021 to 11,487 in August 2021. A high death rate persisted until the end of 2021 [<xref ref-type="bibr" rid="ref6">6</xref>]. In response, the Vietnamese government imposed a lockdown (from July 23 to October 31) on approximately one-third of the country’s population (about 32 million people), including in its most populous cities, Hanoi and Ho Chi Minh City.</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Deaths and confirmed cases of COVID-19 in Vietnam from 2020 to 2021 [<xref ref-type="bibr" rid="ref18">18</xref>].</p>
          </caption>
          <graphic xlink:href="ijmr_v12i1e40883_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Road Trauma Fatalities in Vietnam</title>
        <p>Between 2007 and 2020, the rate of road traffic fatalities decreased by more than 50% from 15.3 to 7 per 100,000 population, an average reduction of 5.4% per annum. The greatest improvements were seen in 2008, 2012, and 2020 (13.0%, 18.0%, and 11.4%, respectively; <xref rid="figure2" ref-type="fig">Figure 2</xref>). We estimated that road traffic mortality rates declined by 12.1% (95% CI 8.9-15.3%) in 2021 relative to this trend. In 2021, there were 5739 deaths, which was a 16.4% decrease from the previous year [<xref ref-type="bibr" rid="ref20">20</xref>]. Thus, there was a further reduction of 4.3% in road trauma deaths in 2021 compared to the previous trend.</p>
        <fig id="figure2" position="float">
          <label>Figure 2</label>
          <caption>
            <p>Number of road traffic fatalities per 100,000 population in Vietnam from 2007 to 2021 [<xref ref-type="bibr" rid="ref12">12</xref>,<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref20">20</xref>]. Arrows indicate government policies that were intentionally or otherwise implemented to address this issue: (1) mandatory helmet use, (2) strengthening of the national traffic safety committee (ie, increased presence of traffic police and increased financial penalties for traffic violations), (3) implementation of the zero-alcohol policy, and (4) COVID-19–related measures.</p>
          </caption>
          <graphic xlink:href="ijmr_v12i1e40883_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>COVID-19’s Impact on Road Trauma</title>
        <p>During the first 2 calendar months of the lockdown, the number of traffic accident deaths decreased by more than 50% from 543 in July to 257 and 254 in August and September 2021, respectively (<xref rid="figure3" ref-type="fig">Figure 3</xref>). It then increased to 377 in October before increasing more substantially to 580 and 680 in November and December, respectively [<xref ref-type="bibr" rid="ref21">21</xref>].</p>
        <fig id="figure3" position="float">
          <label>Figure 3</label>
          <caption>
            <p>Monthly statistics on road accident fatalities from 2018 to 2021 in Vietnam [<xref ref-type="bibr" rid="ref20">20</xref>].</p>
          </caption>
          <graphic xlink:href="ijmr_v12i1e40883_fig3.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>Since the declaration of COVID-19 as a global pandemic by the World Health Organization, the disease has swept through all countries. COVID-19 had minimal impact in Vietnam during the 15 months following its first confirmed case due to the early and decisive policies implemented by the Vietnamese government. However, these early successes were undone by the Delta variant after April 2021. The number of cases and deaths rapidly increased from then onward. Due to vaccine scarcity, the Vietnamese government had to initially rely on lockdown and social distancing policies to control the pandemic. With the availability of community vaccination and its high uptake, lockdown and social distancing measures were relaxed by November 2021. The number of COVID-19 cases reached a new peak, but the fatality rate was only a third of that in August 2021 [<xref ref-type="bibr" rid="ref22">22</xref>]. According to data from the World Health Organization, countries worldwide have experienced these trends regardless of social economic standing [<xref ref-type="bibr" rid="ref23">23</xref>].</p>
      </sec>
      <sec>
        <title>Road Trauma: A Steady Improvement in the Past 14 Years</title>
        <p>Road trauma is a leading cause of death in Vietnam [<xref ref-type="bibr" rid="ref13">13</xref>]. Like other LMICs, common causes include poor road safety and law enforcement, impaired driving, and speeding. Vietnam has been ranked 50 out of 183 recorded countries for road traffic deaths per 100,000 population [<xref ref-type="bibr" rid="ref24">24</xref>]. Consequently, reducing road traffic deaths has been a priority of the Vietnamese government. A range of government decrees, regulations, laws, and policies have been issued and updated to improve the population’s health and financial circumstances. As a result of these initiatives, road trauma deaths have been decreasing by an average of 5.4% per annum over the 2007-2020 period, with the greatest reductions seen in 2008, 2012, and 2020 (<xref rid="figure1" ref-type="fig">Figure 1</xref>). The first reduction coincided with the implementation of mandatory motorcycle helmet use legislation [<xref ref-type="bibr" rid="ref25">25</xref>]. The second was associated with the national traffic safety committee increasing traffic police presence on the road and enforcement of increased financial penalties for traffic violations [<xref ref-type="bibr" rid="ref11">11</xref>]. The third was associated with the introduction of zero-alcohol laws for all drivers and passengers [<xref ref-type="bibr" rid="ref26">26</xref>].</p>
      </sec>
      <sec>
        <title>A “Positive” Side of the Pandemic</title>
        <p>We found that road trauma deaths in Vietnam in 2021 declined at a greater rate compared to the long-term trend. This was likely in response to the COVID-19 pandemic lockdown. In 2021, we found a 16.4 % improvement in road trauma deaths compared with an average 5.4% reduction over the preceding 14 years. This reduction fluctuated month to month. A reason for this distortion was that during the 3 months of lockdown, the number of vehicles on the road decreased by 84%, largely contributing to the total year reduction of 37% [<xref ref-type="bibr" rid="ref27">27</xref>]. Likewise, Yasin et al [<xref ref-type="bibr" rid="ref15">15</xref>] compared April 2020 to April 2019 and found that 32 out of 36 countries had a sharp drop in traffic volume, leading to a substantial reduction in road crashes and road trauma deaths.</p>
        <p>It could be argued that the mortality rate was already declining due to other factors, and the additional decline beyond the preceding trend in 2021 (4.3%) was a delayed effect of the “zero-alcohol” policy from 2020 and not attributable to COVID-19. The temporal relationship of road trauma deaths in relation to the lockdown (<xref rid="figure3" ref-type="fig">Figure 3</xref>) supports our attribution beyond the zero-alcohol policy.</p>
      </sec>
      <sec>
        <title>Effects of the COVID-19 Pandemic on Road Trauma Deaths Globally</title>
        <p>A similar global trend was seen in most HICs where data have been published, with most countries showing a reduction in the annual road accident fatality rate (annual difference percentages) ranging from 5% in Macedonia to 31% in Malta. Some exceptions were seen in several countries with increases observed in Estonia (15%), Finland (4%), Iceland (33%), and the United States (7%) (<xref rid="figure4" ref-type="fig">Figure 4</xref>).</p>
        <p>The explanation for this may be that these countries had not applied public health measures such as lockdowns with as much vigor or as extensively. There may also have been an increased use of private vehicles due to a fear of using public transport [<xref ref-type="bibr" rid="ref36">36</xref>], leading to increased road accidents [<xref ref-type="bibr" rid="ref26">26</xref>,<xref ref-type="bibr" rid="ref27">27</xref>].</p>
        <p>A lesson learned from the COVID-19 pandemic is that one approach to limiting road trauma deaths and injuries is to reduce vehicular traffic. Though this seems a trivial observation and interpretation, it does suggest that the Vietnamese government should prioritize the improvement of public transport such as bus and train systems to reduce private vehicle use and subsequently road trauma and deaths.</p>
        <fig id="figure4" position="float">
          <label>Figure 4</label>
          <caption>
            <p>Comparison of the annual difference percentage in road trauma deaths prior to and during the COVID-19 pandemic in Vietnam and other countries [<xref ref-type="bibr" rid="ref16">16</xref>,<xref ref-type="bibr" rid="ref17">17</xref>,<xref ref-type="bibr" rid="ref27">27</xref>-<xref ref-type="bibr" rid="ref35">35</xref>].</p>
          </caption>
          <graphic xlink:href="ijmr_v12i1e40883_fig4.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>This study would have benefited from additional national and international comparisons. We were limited in performing this analysis due to dissimilarity between national and international data not only for LMICs but also for HICs [<xref ref-type="bibr" rid="ref37">37</xref>]. In this paper, we did not use information from international sources such as the World Health Organization, the World Bank, or the United Nations since the data have been insufficient in the last 15 years and highly variable. For these reasons, we chose original data sourced from the Vietnamese General Statistical Office and Ministry of Health.</p>
      </sec>
      <sec>
        <title>Conclusion</title>
        <p>In 2021, the reduction in road traffic deaths in Vietnam was 3 times greater than the trend over the preceding 14 years. The public health response to the COVID-19 pandemic in Vietnam was associated with this reduction. This has also been observed in HICs but was demonstrated by us for the first time in an LMIC.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group/>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">HIC</term>
          <def>
            <p>high-income country</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">LMIC</term>
          <def>
            <p>low- and middle-income country</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>This work was funded by the Elphinstone Group and Broadreach Holdings Pty Ltd. BTN holds a University of Tasmania scholarship.</p>
    </ack>
    <notes>
      <sec>
        <title>Data Availability</title>
        <p>COVID-19 data can be found on the Ministry of Health website [<xref ref-type="bibr" rid="ref18">18</xref>]. Data on road traffic mortality can be found on the General Statistical Office website [<xref ref-type="bibr" rid="ref19">19</xref>]. All sources are available to the public and free to access.</p>
      </sec>
    </notes>
    <fn-group>
      <fn fn-type="con">
        <p>BTN and MN conceived the idea for the study. BTN, TCQ, and HTN collected the data. BTN and VT drafted the manuscript. BTN and CLB are responsible for the statistical analyses. AP, CLB, TCQ, and HTN revised the manuscript. MN contributed to the critical revision of the manuscript for important intellectual content and approved the final version. All authors have read and approved the final manuscript.</p>
      </fn>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Baloch</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Baloch</surname>
              <given-names>MA</given-names>
            </name>
            <name name-style="western">
              <surname>Zheng</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Pei</surname>
              <given-names>X</given-names>
            </name>
          </person-group>
          <article-title>The coronavirus disease 2019 (COVID-19) pandemic</article-title>
          <source>Tohoku J Exp Med</source>
          <year>2020</year>
          <month>04</month>
          <volume>250</volume>
          <issue>4</issue>
          <fpage>271</fpage>
          <lpage>278</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.1620/tjem.250.271"/>
          </comment>
          <pub-id pub-id-type="doi">10.1620/tjem.250.271</pub-id>
          <pub-id pub-id-type="medline">32321874</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Van Cuong</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Giang</surname>
              <given-names>HTN</given-names>
            </name>
            <name name-style="western">
              <surname>Linh</surname>
              <given-names>LK</given-names>
            </name>
            <name name-style="western">
              <surname>Shah</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Van Sy</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Hung</surname>
              <given-names>TH</given-names>
            </name>
            <name name-style="western">
              <surname>Reda</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Truong</surname>
              <given-names>LN</given-names>
            </name>
            <name name-style="western">
              <surname>Tien</surname>
              <given-names>DX</given-names>
            </name>
            <name name-style="western">
              <surname>Huy</surname>
              <given-names>NT</given-names>
            </name>
          </person-group>
          <article-title>The first Vietnamese case of COVID-19 acquired from China</article-title>
          <source>Lancet Infect Dis</source>
          <year>2020</year>
          <month>04</month>
          <volume>20</volume>
          <issue>4</issue>
          <fpage>408</fpage>
          <lpage>409</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/32085849"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/S1473-3099(20)30111-0</pub-id>
          <pub-id pub-id-type="medline">32085849</pub-id>
          <pub-id pub-id-type="pii">S1473-3099(20)30111-0</pub-id>
          <pub-id pub-id-type="pmcid">PMC7129231</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Van Tan</surname>
              <given-names>L</given-names>
            </name>
          </person-group>
          <article-title>COVID-19 control in Vietnam</article-title>
          <source>Nat Immunol</source>
          <year>2021</year>
          <month>03</month>
          <volume>22</volume>
          <issue>3</issue>
          <fpage>261</fpage>
          <pub-id pub-id-type="doi">10.1038/s41590-021-00882-9</pub-id>
          <pub-id pub-id-type="medline">33627879</pub-id>
          <pub-id pub-id-type="pii">10.1038/s41590-021-00882-9</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>McKee</surname>
              <given-names>KL</given-names>
            </name>
            <name name-style="western">
              <surname>Crandell</surname>
              <given-names>IC</given-names>
            </name>
            <name name-style="western">
              <surname>Hanlon</surname>
              <given-names>AL</given-names>
            </name>
          </person-group>
          <article-title>County-level social distancing and policy impact in the United States: a dynamical systems model</article-title>
          <source>JMIR Public Health Surveill</source>
          <year>2020</year>
          <month>12</month>
          <day>23</day>
          <volume>6</volume>
          <issue>4</issue>
          <fpage>e23902</fpage>
          <pub-id pub-id-type="doi">10.2196/23902</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Vu</surname>
              <given-names>DC</given-names>
            </name>
            <name name-style="western">
              <surname>Nguyen</surname>
              <given-names>TH</given-names>
            </name>
            <name name-style="western">
              <surname>Ho</surname>
              <given-names>TL</given-names>
            </name>
          </person-group>
          <article-title>May the Vietnam response have reduced daily new cases of COVID-19 in the country?</article-title>
          <source>Disaster Med Public Health Prep</source>
          <year>2022</year>
          <month>02</month>
          <day>14</day>
          <fpage>1</fpage>
          <lpage>11</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/35152938"/>
          </comment>
          <pub-id pub-id-type="doi">10.1017/dmp.2022.33</pub-id>
          <pub-id pub-id-type="medline">35152938</pub-id>
          <pub-id pub-id-type="pii">S1935789322000337</pub-id>
          <pub-id pub-id-type="pmcid">PMC8961061</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Minh</surname>
              <given-names>LHN</given-names>
            </name>
            <name name-style="western">
              <surname>Khoi Quan</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Le</surname>
              <given-names>TN</given-names>
            </name>
            <name name-style="western">
              <surname>Khanh</surname>
              <given-names>PNQ</given-names>
            </name>
            <name name-style="western">
              <surname>Huy</surname>
              <given-names>NT</given-names>
            </name>
          </person-group>
          <article-title>COVID-19 timeline of Vietnam: important milestones through four waves of the pandemic and lesson learned</article-title>
          <source>Front Public Health</source>
          <year>2021</year>
          <month>11</month>
          <day>24</day>
          <volume>9</volume>
          <fpage>709067</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/34900885"/>
          </comment>
          <pub-id pub-id-type="doi">10.3389/fpubh.2021.709067</pub-id>
          <pub-id pub-id-type="medline">34900885</pub-id>
          <pub-id pub-id-type="pmcid">PMC8651614</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Guest</surname>
              <given-names>JL</given-names>
            </name>
            <name name-style="western">
              <surname>Del Rio</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Sanchez</surname>
              <given-names>T</given-names>
            </name>
          </person-group>
          <article-title>The three steps needed to end the COVID-19 pandemic: bold public health leadership, rapid innovations, and courageous political will</article-title>
          <source>JMIR Public Health Surveill</source>
          <year>2020</year>
          <month>04</month>
          <day>06</day>
          <volume>6</volume>
          <issue>2</issue>
          <fpage>e19043</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://publichealth.jmir.org/2020/2/e19043/"/>
          </comment>
          <pub-id pub-id-type="doi">10.2196/19043</pub-id>
          <pub-id pub-id-type="medline">32240972</pub-id>
          <pub-id pub-id-type="pii">v6i2e19043</pub-id>
          <pub-id pub-id-type="pmcid">PMC7171587</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Nguyen</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Wong</surname>
              <given-names>ZS</given-names>
            </name>
            <name name-style="western">
              <surname>Wang</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Thanh</surname>
              <given-names>TT</given-names>
            </name>
            <name name-style="western">
              <surname>Van Nguyen</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Gilmour</surname>
              <given-names>S</given-names>
            </name>
          </person-group>
          <article-title>Rapid impact assessments of COVID-19 control measures against the Delta variant and short-term projections of new confirmed cases in Vietnam</article-title>
          <source>J Glob Health</source>
          <year>2021</year>
          <volume>11</volume>
          <fpage>03118</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/34987776"/>
          </comment>
          <pub-id pub-id-type="doi">10.7189/jogh.11.03118</pub-id>
          <pub-id pub-id-type="medline">34987776</pub-id>
          <pub-id pub-id-type="pii">jogh-11-03118</pub-id>
          <pub-id pub-id-type="pmcid">PMC8693161</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Rossiter</surname>
              <given-names>ND</given-names>
            </name>
          </person-group>
          <article-title>Trauma-the forgotten pandemic?</article-title>
          <source>Int Orthop</source>
          <year>2022</year>
          <month>01</month>
          <day>14</day>
          <volume>46</volume>
          <issue>1</issue>
          <fpage>3</fpage>
          <lpage>11</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://europepmc.org/abstract/MED/34519840"/>
          </comment>
          <pub-id pub-id-type="doi">10.1007/s00264-021-05213-z</pub-id>
          <pub-id pub-id-type="medline">34519840</pub-id>
          <pub-id pub-id-type="pii">10.1007/s00264-021-05213-z</pub-id>
          <pub-id pub-id-type="pmcid">PMC8438546</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="web">
          <article-title>Global status report on road safety</article-title>
          <source>World Health Organization</source>
          <year>2018</year>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.who.int/publications/i/item/9789241565684">https://www.who.int/publications/i/item/9789241565684</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Viet Hung</surname>
              <given-names>Khuat</given-names>
            </name>
          </person-group>
          <article-title>For an effective national road safety observatory</article-title>
          <source>National Traffic Safety Committee</source>
          <year>2019</year>
          <month>12</month>
          <day>03</day>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.unescap.org/sites/default/files/For%20an%20effective%20national%20road%20safety%20observatory%20-%20Viet%20Nam.pdf">https://tinyurl.com/3usn7cr7</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="web">
          <article-title>Road safety performance review, Viet Nam: project on strengthening the national road safety management capacities of selected developing countries, and countries with economies in transition</article-title>
          <source>United Nations</source>
          <year>2018</year>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://unece.org/DAM/trans/roadsafe/unda/RSPR_Viet_Nam_FULL_e.pdf">https://unece.org/DAM/trans/roadsafe/unda/RSPR_Viet_Nam_FULL_e.pdf</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Le</surname>
              <given-names>VD</given-names>
            </name>
          </person-group>
          <article-title>Vietnam national road safety goals and action plan: opportunities and challenges</article-title>
          <source>United Nations ESCAP</source>
          <year>2019</year>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://tinyurl.com/5ufmty36">https://tinyurl.com/5ufmty36</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Anh</surname>
              <given-names>TTV</given-names>
            </name>
            <name name-style="western">
              <surname>Burlacu</surname>
              <given-names>AF</given-names>
            </name>
            <name name-style="western">
              <surname>Small</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Paala</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Duc</surname>
              <given-names>NH</given-names>
            </name>
            <name name-style="western">
              <surname>Tri</surname>
              <given-names>LH</given-names>
            </name>
          </person-group>
          <article-title>Road safety data assessment in Vietnam for the establishment of a national road safety observatory</article-title>
          <source>Vietnam Transport Knowledge Series</source>
          <year>2021</year>
          <access-date>2023-01-31</access-date>
          <publisher-loc>Hanoi, Vietnam</publisher-loc>
          <publisher-name>World Bank</publisher-name>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://openknowledge.worldbank.org/handle/10986/35979">https://openknowledge.worldbank.org/handle/10986/35979</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Yasin</surname>
              <given-names>YJ</given-names>
            </name>
            <name name-style="western">
              <surname>Grivna</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Abu-Zidan</surname>
              <given-names>FM</given-names>
            </name>
          </person-group>
          <article-title>Global impact of COVID-19 pandemic on road traffic collisions</article-title>
          <source>World J Emerg Surg</source>
          <year>2021</year>
          <month>09</month>
          <day>28</day>
          <volume>16</volume>
          <issue>1</issue>
          <fpage>51</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://wjes.biomedcentral.com/articles/10.1186/s13017-021-00395-8"/>
          </comment>
          <pub-id pub-id-type="doi">10.1186/s13017-021-00395-8</pub-id>
          <pub-id pub-id-type="medline">34583713</pub-id>
          <pub-id pub-id-type="pii">10.1186/s13017-021-00395-8</pub-id>
          <pub-id pub-id-type="pmcid">PMC8478263</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="web">
          <article-title>Road safety report annual 2020</article-title>
          <source>International Transport Forum</source>
          <year>2020</year>
          <month>10</month>
          <day>26</day>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.itf?oecd.org/sites/default/files/docs/irtad?road?safety?annual?report?2020_0.pdf">https://www.itf?oecd.org/sites/default/files/docs/irtad?road?safety?annual?report?2020_0.pdf</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="web">
          <article-title>Road deaths Australia</article-title>
          <source>Australian Government; Department of Infrastructure, Transport, Regional Development, and Communications</source>
          <year>2020</year>
          <month>04</month>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.bitre.gov.au/sites/default/files/documents/rda_apr_2020.pdf">https://www.bitre.gov.au/sites/default/files/documents/rda_apr_2020.pdf</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="web">
          <article-title>Portal of the Ministry of Health about the COVID-19 pandemic</article-title>
          <source>Ministry of Health, Vietnam</source>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://covid19.gov.vn/ban-tin-covid-19.htm">https://covid19.gov.vn/ban-tin-covid-19.htm</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="web">
          <article-title>Search results for "social economic situation report by years"</article-title>
          <source>General Statistics Office, Vietnam</source>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.gso.gov.vn/en/?s=SOCIO-ECONOMIC+SITUATION+REPORT&#38;lang=en">https://www.gso.gov.vn/en/?s=SOCIO-ECONOMIC+SITUATION+REPORT&#38;lang=en</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Nguyen</surname>
              <given-names>TTH</given-names>
            </name>
          </person-group>
          <article-title>Press release socio-economic situation in the fourth quarter and 2021</article-title>
          <source>General Statistics Office, Vietnam</source>
          <year>2021</year>
          <month>12</month>
          <day>29</day>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.gso.gov.vn/en/data-and-statistics/2022/01/press-release-socio-economic-situation-in-the-fourth-quarter-and-2021/">https://www.gso.gov.vn/en/data-and-statistics/2022/01/press-release-socio-economic-situation-in-the-fourth-quarter-and-2021/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="web">
          <article-title>Vietnam locks down capital Hanoi as COVID-19 infections soar</article-title>
          <source>Al Jazeera</source>
          <year>2020</year>
          <month>07</month>
          <day>24</day>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.aljazeera.com/news/2021/7/24/vietnam-locks-down-capital-hanoi-as-covid-19-infections-soar">https://www.aljazeera.com/news/2021/7/24/vietnam-locks-down-capital-hanoi-as-covid-19-infections-soar</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Mathieu</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Ritchie</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Rodés-Guirao</surname>
              <given-names>L</given-names>
            </name>
            <name name-style="western">
              <surname>Appel</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Giattino</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Hasell</surname>
              <given-names>J</given-names>
            </name>
            <name name-style="western">
              <surname>Macdonald</surname>
              <given-names>B</given-names>
            </name>
          </person-group>
          <article-title>Coronavirus (COVID-19) vaccinations</article-title>
          <source>Our World in Data</source>
          <year>2020</year>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://ourworldindata.org/covid-vaccinations?country=OWID_WRL">https://ourworldindata.org/covid-vaccinations?country=OWID_WRL</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="web">
          <article-title>WHO coronavirus (COVID-19) dashboard</article-title>
          <source>World Health Organization</source>
          <year>2023</year>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://covid19.who.int/">https://covid19.who.int/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="web">
          <article-title>Road traffic accidents</article-title>
          <source>World Life Expectancy</source>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.worldlifeexpectancy.com/">https://www.worldlifeexpectancy.com/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Olson</surname>
              <given-names>Zachary</given-names>
            </name>
            <name name-style="western">
              <surname>Staples</surname>
              <given-names>JA</given-names>
            </name>
            <name name-style="western">
              <surname>Mock</surname>
              <given-names>Charles</given-names>
            </name>
            <name name-style="western">
              <surname>Nguyen</surname>
              <given-names>Nam Phuong</given-names>
            </name>
            <name name-style="western">
              <surname>Bachani</surname>
              <given-names>Abdulgafoor M</given-names>
            </name>
            <name name-style="western">
              <surname>Nugent</surname>
              <given-names>Rachel</given-names>
            </name>
            <name name-style="western">
              <surname>Verguet</surname>
              <given-names>Stéphane</given-names>
            </name>
          </person-group>
          <article-title>Helmet regulation in Vietnam: impact on health, equity and medical impoverishment</article-title>
          <source>Inj Prev</source>
          <year>2016</year>
          <month>08</month>
          <volume>22</volume>
          <issue>4</issue>
          <fpage>233</fpage>
          <lpage>8</lpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="http://injuryprevention.bmj.com/lookup/pmidlookup?view=long&#38;pmid=26728008"/>
          </comment>
          <pub-id pub-id-type="doi">10.1136/injuryprev-2015-041650</pub-id>
          <pub-id pub-id-type="medline">26728008</pub-id>
          <pub-id pub-id-type="pii">injuryprev-2015-041650</pub-id>
          <pub-id pub-id-type="pmcid">PMC4975813</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Park</surname>
              <given-names>K</given-names>
            </name>
          </person-group>
          <article-title>New law on prevention and control of alcohol related harms in Vietnam</article-title>
          <source>J Glob Health Sci</source>
          <year>2019</year>
          <volume>1</volume>
          <issue>2</issue>
          <pub-id pub-id-type="doi">10.35500/jghs.2019.1.e49</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="web">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Pham</surname>
              <given-names>HC</given-names>
            </name>
          </person-group>
          <article-title>Impacts of COVID-19 on urban mobility: experience of major cities in Vietnam</article-title>
          <source>Transport Development and Strategy Institute, United Nations ESCAP</source>
          <year>2020</year>
          <month>11</month>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.unescap.org/sites/default/files/5_COVID-19%20and%20Mobility%20Experience%20of%20Major%20Cities%20in%20Viet%20Nam.pdf">https://www.unescap.org/sites/default/files/5_COVID-19%20and%20Mobility%20Experience%20of%20Major%20Cities%20in%20Viet%20Nam.pdf</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="web">
          <article-title>Mobility and transport</article-title>
          <source>European Commission</source>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://ec.europa.eu/transport/modes/road/news/2021?0420?road?safety_en">https://ec.europa.eu/transport/modes/road/news/2021?0420?road?safety_en</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="web">
          <article-title>Early estimate of motor vehicle traffic fatalities in 2020</article-title>
          <source>US Department of Transportation, National Highway Traffic Safety Administration</source>
          <year>2021</year>
          <month>06</month>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://crashstats.nhtsa.dot.gov/Api/Public/ViewPublication/813118">https://crashstats.nhtsa.dot.gov/Api/Public/ViewPublication/813118</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="web">
          <article-title>Fatalities for 2020: annual statistics for Western Balkans</article-title>
          <source>Transport Community Permanent Secretariat</source>
          <year>2021</year>
          <month>04</month>
          <day>15</day>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.mit-ks.net/repository/docs/2021_04_22_081823_Annual-Statistics-2020.pdf">https://www.mit-ks.net/repository/docs/2021_04_22_081823_Annual-Statistics-2020.pdf</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="web">
          <article-title>Motor vehicle</article-title>
          <source>National Safety Council</source>
          <year>2021</year>
          <access-date>2023-01-31</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://injuryfacts.nsc.org/motor?vehicle/overview/preliminary?estimates/">https://injuryfacts.nsc.org/motor?vehicle/overview/preliminary?estimates/</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Katrakazas</surname>
              <given-names>C</given-names>
            </name>
            <name name-style="western">
              <surname>Michelaraki</surname>
              <given-names>E</given-names>
            </name>
            <name name-style="western">
              <surname>Sekadakis</surname>
              <given-names>M</given-names>
            </name>
            <name name-style="western">
              <surname>Yannis</surname>
              <given-names>G</given-names>
            </name>
          </person-group>
          <article-title>A descriptive analysis of the effect of the COVID-19 pandemic on driving behavior and road safety</article-title>
          <source>Transp Res Interdiscip Perspect</source>
          <year>2020</year>
          <month>09</month>
          <volume>7</volume>
          <fpage>100186</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2590-1982(20)30097-X"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.trip.2020.100186</pub-id>
          <pub-id pub-id-type="medline">34173462</pub-id>
          <pub-id pub-id-type="pii">S2590-1982(20)30097-X</pub-id>
          <pub-id pub-id-type="pmcid">PMC7395634</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="web">
          <article-title>2020 road deaths down on 2019</article-title>
          <source>New Zealand Police</source>
          <year>2021</year>
          <month>01</month>
          <day>01</day>
          <access-date>2021-05-25</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.police.govt.nz/news/release/2020-road-deaths-down-2019">https://www.police.govt.nz/news/release/2020-road-deaths-down-2019</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Jacob</surname>
              <given-names>S</given-names>
            </name>
            <name name-style="western">
              <surname>Mwagiru</surname>
              <given-names>D</given-names>
            </name>
            <name name-style="western">
              <surname>Thakur</surname>
              <given-names>I</given-names>
            </name>
            <name name-style="western">
              <surname>Moghadam</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Oh</surname>
              <given-names>T</given-names>
            </name>
            <name name-style="western">
              <surname>Hsu</surname>
              <given-names>J</given-names>
            </name>
          </person-group>
          <article-title>Impact of societal restrictions and lockdown on trauma admissions during the COVID-19 pandemic: a single-centre cross-sectional observational study</article-title>
          <source>ANZ J Surg</source>
          <year>2020</year>
          <month>11</month>
          <volume>90</volume>
          <issue>11</issue>
          <fpage>2227</fpage>
          <lpage>2231</lpage>
          <pub-id pub-id-type="doi">10.1111/ans.16307</pub-id>
          <pub-id pub-id-type="medline">32894624</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="web">
          <article-title>Road traffic estimates in Great Britain: 2020</article-title>
          <source>Gov.uk, Department for Transport</source>
          <year>2021</year>
          <month>04</month>
          <day>28</day>
          <access-date>2021-06-05</access-date>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://www.gov.uk/government/statistics/road-traffic-estimates-in-great-britain-2020">https://www.gov.uk/government/statistics/road-traffic-estimates-in-great-britain-2020</ext-link>
          </comment>
        </nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Pawar</surname>
              <given-names>DS</given-names>
            </name>
            <name name-style="western">
              <surname>Yadav</surname>
              <given-names>AK</given-names>
            </name>
            <name name-style="western">
              <surname>Akolekar</surname>
              <given-names>N</given-names>
            </name>
            <name name-style="western">
              <surname>Velaga</surname>
              <given-names>NR</given-names>
            </name>
          </person-group>
          <article-title>Impact of physical distancing due to novel coronavirus (SARS-CoV-2) on daily travel for work during transition to lockdown</article-title>
          <source>Transp Res Interdiscip Perspect</source>
          <year>2020</year>
          <month>09</month>
          <volume>7</volume>
          <fpage>100203</fpage>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://linkinghub.elsevier.com/retrieve/pii/S2590-1982(20)30114-7"/>
          </comment>
          <pub-id pub-id-type="doi">10.1016/j.trip.2020.100203</pub-id>
          <pub-id pub-id-type="medline">34173467</pub-id>
          <pub-id pub-id-type="pii">S2590-1982(20)30114-7</pub-id>
          <pub-id pub-id-type="pmcid">PMC7437436</pub-id>
        </nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="journal">
          <person-group person-group-type="author">
            <name name-style="western">
              <surname>Razzaghi</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Soori</surname>
              <given-names>H</given-names>
            </name>
            <name name-style="western">
              <surname>Abadi</surname>
              <given-names>A</given-names>
            </name>
            <name name-style="western">
              <surname>Khosravi</surname>
              <given-names>A</given-names>
            </name>
          </person-group>
          <article-title>World Health Organization's estimates of death related to road traffic crashes and their discrepancy with other countries' national report</article-title>
          <source>J Inj Violence Res</source>
          <year>2020</year>
          <month>10</month>
          <day>06</day>
          <volume>12</volume>
          <issue>3</issue>
          <comment>
            <ext-link ext-link-type="uri" xlink:type="simple" xlink:href="https://doi.org/10.5249/jivr.v12i3.1425"/>
          </comment>
          <pub-id pub-id-type="doi">10.5249/jivr.v12i3.1425</pub-id>
          <pub-id pub-id-type="medline">33021247</pub-id>
          <pub-id pub-id-type="pii">1425</pub-id>
        </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
